1999
Endogenous DA‐mediated feedback inhibition of DA neurons: Involvement of both D1‐ and D2‐like receptors
Shi W, Pun C, Smith P, Bunney B. Endogenous DA‐mediated feedback inhibition of DA neurons: Involvement of both D1‐ and D2‐like receptors. Synapse 1999, 35: 111-119. PMID: 10611636, DOI: 10.1002/(sici)1098-2396(200002)35:2<111::aid-syn3>3.0.co;2-7.Peer-Reviewed Original ResearchConceptsDA neuronsLike receptorsDA cellsEndogenous DAChloral hydrate-anesthetized ratsNigral DA cellsD2-like receptorsSingle-unit recordingsCerveau isolé preparationFeedback inhibitionParkinsonian animalsAntagonist racloprideAntagonist SCH23390DA releaseEndogenous dopamineD-amphetamineParkinson's diseaseUnit recordingsSCH23390Receptor activationBaseline activityReceptorsChloral hydrateNeuronsConcurrent activation
1997
D1–D2 Interaction in Feedback Control of Midbrain Dopamine Neurons
Shi W, Smith P, Pun C, Millet B, Bunney B. D1–D2 Interaction in Feedback Control of Midbrain Dopamine Neurons. Journal Of Neuroscience 1997, 17: 7988-7994. PMID: 9315916, PMCID: PMC6793911, DOI: 10.1523/jneurosci.17-20-07988.1997.Peer-Reviewed Original ResearchConceptsD2-like receptorsDA cellsDA autoreceptorsDA neuronsD1 agonistLow dosesDopamine D1-like receptorsD1 inhibitionD1 effectNigral DA cellsMidbrain DA neuronsD2 agonist quinpiroleD1-like receptorsDA receptor subtypesMidbrain dopamine neuronsOnly low dosesDA receptorsEndogenous DAAgonist quinpiroleD2 agonistIntranigral applicationDopamine neuronsReceptor subtypesRat preparationTarget neurons
1991
Midbrain dopamine system electrophysiological functioning: A review and new hypothesis
Bunney B, Chiodo L, Grace A. Midbrain dopamine system electrophysiological functioning: A review and new hypothesis. Synapse 1991, 9: 79-94. PMID: 1821487, DOI: 10.1002/syn.890090202.Peer-Reviewed Original Research
1978
d-Amphetamine-induced depression of central dopamine neurons: Evidence for mediation by both autoreceptors and a striato-nigral feedback pathway
Bunney B, Aghajanian G. d-Amphetamine-induced depression of central dopamine neurons: Evidence for mediation by both autoreceptors and a striato-nigral feedback pathway. Naunyn-Schmiedeberg's Archives Of Pharmacology 1978, 304: 255-261. PMID: 714182, DOI: 10.1007/bf00507966.Peer-Reviewed Original ResearchConceptsDA cellsSubstantia nigraFeedback pathwaysCentral dopamine neuronsIntravenous d-amphetamineNon-convulsant dosesPicrotoxin-treated animalsKainic acid injectionRelease of GABAActivity of dopamineNon-lesioned animalsSingle-cell recordingsDA autoreceptorsDendrodendritic synapsesMicroiontophoretic techniquesAfferent terminalsDepressant effectUnlesioned animalsDopamine neuronsGABA antagonistsAnesthetized ratsD-amphetamineCaudate nucleusAcid injectionHigh doses
1977
Dopamine “Autoreceptors”: Pharmacological characterization by microiontophoretic single cell recording studies
Aghajanian G, Bunney B. Dopamine “Autoreceptors”: Pharmacological characterization by microiontophoretic single cell recording studies. Naunyn-Schmiedeberg's Archives Of Pharmacology 1977, 297: 1-7. PMID: 193046, DOI: 10.1007/bf00508803.Peer-Reviewed Original ResearchConceptsDA neuronsDepressant effectDA agonist apomorphineWeak depressant actionSingle-cell recording studiesSingle-cell recordingsAgonist apomorphineDA agonistsMicroiontophoretic applicationMicroiontophoretic techniquesSubstantia nigraDepressant actionDopamine neuronsSingle dopamine neuronsPharmacological characterizationCatecholamine receptorsΒ-adrenoreceptorsCell recordingsCatecholamine agonistsRecording studiesNeuronsAutoreceptorsAntagonist trifluoperazineAgonistsSelective responsiveness
1976
d-Amphetamine-Induced Inhibition of Central Dopaminergic Neurons: Mediation by a Striato-Nigral Feedback Pathway
Bunney B, Achajanian G. d-Amphetamine-Induced Inhibition of Central Dopaminergic Neurons: Mediation by a Striato-Nigral Feedback Pathway. Science 1976, 192: 391-393. PMID: 1257777, DOI: 10.1126/science.1257777.Peer-Reviewed Original ResearchConceptsD-amphetamineDepressant effectDopaminergic cell activityIntravenous d-amphetamineCentral dopaminergic neuronsStriato-nigral pathwayNeuronal feedback loopMicroiontophoretic applicationDopaminergic neuronsDopaminergic cellsCell activitySignificant slowingFeedback pathwaysPrevious dataCellsLesionsPathwayNeurons