1999
Endogenous DA‐mediated feedback inhibition of DA neurons: Involvement of both D1‐ and D2‐like receptors
Shi W, Pun C, Smith P, Bunney B. Endogenous DA‐mediated feedback inhibition of DA neurons: Involvement of both D1‐ and D2‐like receptors. Synapse 1999, 35: 111-119. PMID: 10611636, DOI: 10.1002/(sici)1098-2396(200002)35:2<111::aid-syn3>3.0.co;2-7.Peer-Reviewed Original ResearchConceptsDA neuronsLike receptorsDA cellsEndogenous DAChloral hydrate-anesthetized ratsNigral DA cellsD2-like receptorsSingle-unit recordingsCerveau isolé preparationFeedback inhibitionParkinsonian animalsAntagonist racloprideAntagonist SCH23390DA releaseEndogenous dopamineD-amphetamineParkinson's diseaseUnit recordingsSCH23390Receptor activationBaseline activityReceptorsChloral hydrateNeuronsConcurrent activation
1997
D1–D2 Interaction in Feedback Control of Midbrain Dopamine Neurons
Shi W, Smith P, Pun C, Millet B, Bunney B. D1–D2 Interaction in Feedback Control of Midbrain Dopamine Neurons. Journal Of Neuroscience 1997, 17: 7988-7994. PMID: 9315916, PMCID: PMC6793911, DOI: 10.1523/jneurosci.17-20-07988.1997.Peer-Reviewed Original ResearchConceptsD2-like receptorsDA cellsDA autoreceptorsDA neuronsD1 agonistLow dosesDopamine D1-like receptorsD1 inhibitionD1 effectNigral DA cellsMidbrain DA neuronsD2 agonist quinpiroleD1-like receptorsDA receptor subtypesMidbrain dopamine neuronsOnly low dosesDA receptorsEndogenous DAAgonist quinpiroleD2 agonistIntranigral applicationDopamine neuronsReceptor subtypesRat preparationTarget neurons
1989
Pharmacological characterization of the receptor mediating electrophysiological responses to dopamine in the rat medial prefrontal cortex: a microiontophoretic study.
Sesack S, Bunney B. Pharmacological characterization of the receptor mediating electrophysiological responses to dopamine in the rat medial prefrontal cortex: a microiontophoretic study. Journal Of Pharmacology And Experimental Therapeutics 1989, 248: 1323-33. PMID: 2564893.Peer-Reviewed Original ResearchConceptsRat medial prefrontal cortexMedial prefrontal cortexGamma-aminobutyric acidD2-selective agonistsSelective agonistPrefrontal cortexPFC neuronsInhibitory effectSelective antagonistExtracellular single-unit recordingsD1-selective agonistsSingle-unit recordingsD1-selective antagonistD2-selective antagonistWeak antagonist activityMicroiontophoretic studyMicroiontophoretic techniquesSuperficial laminaeIontophoretic applicationLY171555Pharmacological characterizationInhibitory responsesMajority of cellsPharmacological characteristicsPharmacological profile