1994
The NMDA glycine site antagonist (+)-HA-966 selectively regulates conditioned stress-induced metabolic activation of the mesoprefrontal cortical dopamine but not serotonin systems: a behavioral, neuroendocrine, and neurochemical study in the rat
Goldstein L, Rasmusson A, Bunney B, Roth R. The NMDA glycine site antagonist (+)-HA-966 selectively regulates conditioned stress-induced metabolic activation of the mesoprefrontal cortical dopamine but not serotonin systems: a behavioral, neuroendocrine, and neurochemical study in the rat. Journal Of Neuroscience 1994, 14: 4937-4950. PMID: 8046462, PMCID: PMC6577203, DOI: 10.1523/jneurosci.14-08-04937.1994.Peer-Reviewed Original ResearchConceptsStress-induced increaseNMDA glycine-site antagonistsDA utilizationGlycine modulatory siteGlycine site antagonistHA-966Conditioned stressPrefrontal cortexCortical dopamineSite antagonistNucleus accumbensControl animalsModulatory siteMedial prefrontal cortical dopamineLateral prefrontal cortexPrefrontal cortical dopamineSerum corticosterone levelsNMDA receptor complexPost-traumatic stress disorderMedial prefrontal cortexNeurotransmitter ratiosRegional dopamineSerotonin utilizationSerum corticosteroneNMDA receptors
1982
A modification of the rapid glyoxylic acid technique permits visualization of serotonergic and hypothalamic dopaminergic neurons
Rassmussen S, Bunney B. A modification of the rapid glyoxylic acid technique permits visualization of serotonergic and hypothalamic dopaminergic neurons. Journal Of Neuroscience Methods 1982, 6: 139-144. PMID: 6750255, DOI: 10.1016/0165-0270(82)90024-3.Peer-Reviewed Original ResearchConceptsGlyoxylic acid techniqueHypothalamic dopaminergic neuronsTryptophan hydroxylase inhibitorHypothalamic cell groupsTryptophan pretreatmentCatecholaminergic neuronsDopaminergic neuronsHypothalamic neuronsPara-chlorophenylalanineDendritic fieldsSerotonergic systemCatecholamine systemsColchicine administrationHydroxylase inhibitorColchicine pretreatmentCell groupsNeuronsAcid techniqueMethod of choiceReliable visualizationPretreatmentDopaminergicHistofluorescenceImmunocytohistochemistryAdministrationEffect of cholecystokinin of the activity of midbrain dopaminergic neurons.
Bunney B, Grace A, Hommer D, Skirboll L. Effect of cholecystokinin of the activity of midbrain dopaminergic neurons. Advances In Biochemical Psychopharmacology 1982, 33: 429-36. PMID: 7124507.Peer-Reviewed Original Research
1976
The precise localization of nigral afferents in the rat as determined by a retrograde tracing technique
Bunney B, Aghajanian G. The precise localization of nigral afferents in the rat as determined by a retrograde tracing technique. Brain Research 1976, 117: 423-435. PMID: 990939, DOI: 10.1016/0006-8993(76)90751-4.Peer-Reviewed Original Research
1975
Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine
Svensson T, Bunney B, Aghajanian G. Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine. Brain Research 1975, 92: 291-306. PMID: 1174954, DOI: 10.1016/0006-8993(75)90276-0.Peer-Reviewed Original ResearchConceptsNE neuronsAgonist clonidineHigh dosesMidbrain dorsal raphe nucleusAlpha-adrenergic agonist clonidineSingle-unit recording techniquesBrain NE neuronsClonidine-induced depressionDorsal raphe nucleusAdrenergic agonist clonidineBrain norepinephrineRaphe neuronsIntravenous clonidineAdrenergic transmissionSerotonergic neuronsDepressant effectDopaminergic neuronsRaphe nucleusSpontaneous firingLocus coeruleusClonidineLow doseL-amphetamineAdrenergic receptorsNeurons