Functional Coupling between the Prefrontal Cortex and Dopamine Neurons in the Ventral Tegmental Area
Gao M, Liu C, Yang S, Jin G, Bunney B, Shi W. Functional Coupling between the Prefrontal Cortex and Dopamine Neurons in the Ventral Tegmental Area. Journal Of Neuroscience 2007, 27: 5414-5421. PMID: 17507563, PMCID: PMC6672349, DOI: 10.1523/jneurosci.5347-06.2007.Peer-Reviewed Original ResearchConceptsVentral tegmental areaVTA DA neuronsDA neuronsPrefrontal cortexPFC neuronsDopamine neuronsTegmental areaAction potential-dependent DA releaseSlow oscillationsChloral hydrate-anesthetized ratsIntra-PFC infusionsFunctional couplingPFC terminalsVTA DAGlutamate releaseDA releaseExcitatory influenceRelay neuronsInhibitory influenceCell activityBrain functionNeuronsImportant new insightsCortexMultiple pathways