1983
Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—1. Identification and characterization
Grace A, Bunney B. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—1. Identification and characterization. Neuroscience 1983, 10: 301-315. PMID: 6633863, DOI: 10.1016/0306-4522(83)90135-5.Peer-Reviewed Original ResearchConceptsAction potentialsDopamine neuronsDopamine cellsGlyoxylic acid-induced catecholamine fluorescenceInput resistanceDopamine synthesizing enzymePostsynaptic target areasIntracellular dopamine contentNigral dopamine cellsPossible modulatory effectDopamine-containing cellsIntracellular dopamine concentrationSame inhibitory effectHigh input resistanceInitial segmentAntidromic activationDopaminergic neuronsDopamine contentIntracellular recordingsDopamine synthesisCaudate nucleusElectrophysiological characteristicsTyrosine hydroxylaseCatecholamine fluorescenceModulatory effects
1973
Comparison of Effects of L-Dopa, Amphetamine and Apomorphine on Firing Rate of Rat Dopaminergic Neurones
BUNNEY B, AGHAJANIAN G, ROTH R. Comparison of Effects of L-Dopa, Amphetamine and Apomorphine on Firing Rate of Rat Dopaminergic Neurones. Nature 1973, 245: 123-125. PMID: 4518113, DOI: 10.1038/newbio245123a0.Peer-Reviewed Original ResearchConceptsDopamine receptorsAdjacent ventral tegmental areaL-DOPASubstantia nigra zona compactaFiring rateVentral tegmental areaAvailability of dopamineAromatic amino acid decarboxylaseDopamine-containing cellsAmount of dopamineComparison of effectsZona compactaTegmental areaD-amphetamineDopaminergic neuronesAmino acid decarboxylaseReceptor stimulationAcid decarboxylaseDopamineReceptorsApomorphineDrugsStimulationFeedback inhibitionCompacta