Rho GTPase controls invagination and cohesive migration of the Drosophila salivary gland through Crumbs and Rho-kinase
Xu N, Keung B, Myat M. Rho GTPase controls invagination and cohesive migration of the Drosophila salivary gland through Crumbs and Rho-kinase. Developmental Biology 2008, 321: 88-100. PMID: 18585373, DOI: 10.1016/j.ydbio.2008.06.007.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell PolarityDrosophilaDrosophila ProteinsEmbryo, NonmammalianEpithelial CellsMembrane ProteinsRho GTP-Binding ProteinsRho-Associated KinasesSalivary GlandsConceptsRho1 activityRho GTPaseCircular visceral mesodermDrosophila salivary glandsSalivary gland migrationCell shape changesLive-imaging analysisSmall GTPase RhoRho-kinaseZygotic functionApical proteinsVisceral mesodermCohesive migrationEpithelial morphogenesisGland migrationGTPase activityApical localizationDownstream effectorsGTPase RhoAtypical PKCApical constrictionSalivary gland epitheliumProper developmentSimple epitheliaGland cells