Differential effects of tricyclic antidepressant drugs on membrane dynamics—a fluorescence spectroscopic study
Sanganahalli B, Joshi P, Joshi N. Differential effects of tricyclic antidepressant drugs on membrane dynamics—a fluorescence spectroscopic study. Life Sciences 2000, 68: 81-90. PMID: 11132248, DOI: 10.1016/s0024-3205(00)00918-8.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntidepressive Agents, TricyclicCell MembraneKineticsLipid BilayersMaleRatsRats, Sprague-DawleySodium-Potassium-Exchanging ATPaseSpectrometry, FluorescenceSynaptosomesConceptsDimyristoyl phosphatidyl cholineSteady state anisotropyAntidepressant drugsTime-dependent anisotropyDecay of anisotropyFluorescence decay timeSynaptosomal membranesActivity of Na+-K+-ATPaseTricyclic antidepressant drugsNa+-K+-ATPaseDecay timeAntidepressant drug amitriptylineNortriptyline treatmentLimiting anisotropyRat brain synaptosomesTricyclic antidepressant drug amitriptylineDesipramineAmitriptylineCase of amitriptylineImipramineNortriptylineRat brainAnisotropyBrain synaptosomesTime-dependent fluorescence spectroscopy