2021
Supraspinal Sensorimotor and Pain-Related Reorganization after a Hemicontusion Rat Cervical Spinal Cord Injury
Sanganahalli BG, Chitturi J, Herman P, Elkabes S, Heary R, Hyder F, Kannurpatti SS. Supraspinal Sensorimotor and Pain-Related Reorganization after a Hemicontusion Rat Cervical Spinal Cord Injury. Journal Of Neurotrauma 2021, 38: 3393-3405. PMID: 34714150, PMCID: PMC8713267, DOI: 10.1089/neu.2021.0190.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBehavior, AnimalCervical CordDisease Models, AnimalFemaleMagnetic Resonance ImagingPainRatsSomatosensory CortexSpinal Cord InjuriesConceptsSpinal cord injuryCervical spinal cord injuryAnterior cingulate cortexFunctional magnetic resonance imagingPre-frontal cortexNociceptive regionsCord injuryPresence of painSecondary somatosensory cortexFunctional connectivity densityElectrical forepaw stimulationFemale adult ratsTranslational animal modelsMost cortical regionsMagnetic resonance imagingDiscernable lesionsIpsilesional forelimbKdyn forceRSFC decreasesRsFC increasesSupraspinal changesMotor recoveryThermal hyperalgesiaT2 lesionsPain behavior
2016
Metabolic demands of neural-hemodynamic associated and disassociated areas in brain
Sanganahalli BG, Herman P, Rothman DL, Blumenfeld H, Hyder F. Metabolic demands of neural-hemodynamic associated and disassociated areas in brain. Cerebrovascular And Brain Metabolism Reviews 2016, 36: 1695-1707. PMID: 27562867, PMCID: PMC5076793, DOI: 10.1177/0271678x16664531.Peer-Reviewed Original ResearchConceptsVentral posterolateral thalamic nucleusFunctional magnetic resonance imagingMulti-unit activityLocal field potentialsMetabolic demandsPosterolateral thalamic nucleusBlood oxygenation level-dependent (BOLD) responseSensory-evoked responsesCortical local field potentialsThalamic local field potentialsMagnetic resonance imagingLevel-dependent responsesSimilar metabolic demandThalamic nucleiForelimb cortexBlood flowBlood volumeCBV responseResonance imagingLatency differenceHemodynamicsBOLD signalOxidative metabolismDifferent metabolic demandsField potentials
2013
Quantitative basis for neuroimaging of cortical laminae with calibrated functional MRI
Herman P, Sanganahalli BG, Blumenfeld H, Rothman DL, Hyder F. Quantitative basis for neuroimaging of cortical laminae with calibrated functional MRI. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 15115-15120. PMID: 23980158, PMCID: PMC3773779, DOI: 10.1073/pnas.1307154110.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood VolumeCerebrovascular CirculationFunctional NeuroimagingMagnetic Resonance ImagingModels, NeurologicalOxygenRatsSomatosensory CortexConceptsCerebral blood volumeLocal field potentialsMultiunit activitySomatosensory cortexCortical laminaeBlood oxygenation level-dependent (BOLD) signalRat somatosensory cortexLevel-dependent signalNeurometabolic couplingCerebral cortexSuperficial laminaeCBF changesDeep laminaeMagnetic resonance imaging dataBlood flowQuantitative neuroimagingBlood volumeFunctional MRISensory stimulationBOLD signalOxidative metabolismCortexLayer-specific responsesMetabolic measurementsField potentials
2009
Oxidative Neuroenergetics in Event-Related Paradigms
Sanganahalli BG, Herman P, Blumenfeld H, Hyder F. Oxidative Neuroenergetics in Event-Related Paradigms. Journal Of Neuroscience 2009, 29: 1707-1718. PMID: 19211878, PMCID: PMC2760964, DOI: 10.1523/jneurosci.5549-08.2009.Peer-Reviewed Original Research
2007
Energetics of neuronal signaling and fMRI activity
Maandag NJ, Coman D, Sanganahalli BG, Herman P, Smith AJ, Blumenfeld H, Shulman RG, Hyder F. Energetics of neuronal signaling and fMRI activity. Proceedings Of The National Academy Of Sciences Of The United States Of America 2007, 104: 20546-20551. PMID: 18079290, PMCID: PMC2154468, DOI: 10.1073/pnas.0709515104.Peer-Reviewed Original ResearchConceptsRSN activityContralateral S1FMRI activationBaseline stateContralateral primary somatosensory cortexPrimary somatosensory cortexSomatosensory cortexIntracortical interactionsFiring rateNeuronal signalingFMRI activityEnsemble activityEnsemble firingStimulationHalothaneCortexNeuronsBaselineActivationFMRI dataLarge majorityAnesthesiaActivityRats