Supraspinal Sensorimotor and Pain-Related Reorganization after a Hemicontusion Rat Cervical Spinal Cord Injury
Sanganahalli BG, Chitturi J, Herman P, Elkabes S, Heary R, Hyder F, Kannurpatti SS. Supraspinal Sensorimotor and Pain-Related Reorganization after a Hemicontusion Rat Cervical Spinal Cord Injury. Journal Of Neurotrauma 2021, 38: 3393-3405. PMID: 34714150, PMCID: PMC8713267, DOI: 10.1089/neu.2021.0190.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCervical spinal cord injuryAnterior cingulate cortexFunctional magnetic resonance imagingPre-frontal cortexNociceptive regionsCord injuryPresence of painSecondary somatosensory cortexFunctional connectivity densityElectrical forepaw stimulationFemale adult ratsTranslational animal modelsMost cortical regionsMagnetic resonance imagingDiscernable lesionsIpsilesional forelimbKdyn forceRSFC decreasesRsFC increasesSupraspinal changesMotor recoveryThermal hyperalgesiaT2 lesionsPain behavior