2016
Metabolic demands of neural-hemodynamic associated and disassociated areas in brain
Sanganahalli BG, Herman P, Rothman DL, Blumenfeld H, Hyder F. Metabolic demands of neural-hemodynamic associated and disassociated areas in brain. Cerebrovascular And Brain Metabolism Reviews 2016, 36: 1695-1707. PMID: 27562867, PMCID: PMC5076793, DOI: 10.1177/0271678x16664531.Peer-Reviewed Original ResearchConceptsVentral posterolateral thalamic nucleusFunctional magnetic resonance imagingMulti-unit activityLocal field potentialsMetabolic demandsPosterolateral thalamic nucleusBlood oxygenation level-dependent (BOLD) responseSensory-evoked responsesCortical local field potentialsThalamic local field potentialsMagnetic resonance imagingLevel-dependent responsesSimilar metabolic demandThalamic nucleiForelimb cortexBlood flowBlood volumeCBV responseResonance imagingLatency differenceHemodynamicsBOLD signalOxidative metabolismDifferent metabolic demandsField potentialsChapter 5 New horizons in neurometabolic and neurovascular coupling from calibrated fMRI
Shu CY, Sanganahalli BG, Coman D, Herman P, Hyder F. Chapter 5 New horizons in neurometabolic and neurovascular coupling from calibrated fMRI. Progress In Brain Research 2016, 225: 99-122. PMID: 27130413, DOI: 10.1016/bs.pbr.2016.02.003.Peer-Reviewed Original ResearchConceptsNeurovascular couplingFunctional MRINeuronal activityBlood oxygenation level-dependent (BOLD) signalFunctional brain activationLevel-dependent signalNeurometabolic couplingEffective therapyBlood flowNeuroimaging toolsHealth conditionsPowerful neuroimaging toolBrain activationBOLD signalNeural activityBOLD contrastMetabolic demandsOxygen consumptionDependent signalsTherapyMicrovesselsMRIActivityBiomarkers
2015
Brain region and activity-dependent properties of M for calibrated fMRI
Shu CY, Herman P, Coman D, Sanganahalli BG, Wang H, Juchem C, Rothman DL, de Graaf RA, Hyder F. Brain region and activity-dependent properties of M for calibrated fMRI. NeuroImage 2015, 125: 848-856. PMID: 26529646, PMCID: PMC4691415, DOI: 10.1016/j.neuroimage.2015.10.083.Peer-Reviewed Original Research
2013
Quantitative basis for neuroimaging of cortical laminae with calibrated functional MRI
Herman P, Sanganahalli BG, Blumenfeld H, Rothman DL, Hyder F. Quantitative basis for neuroimaging of cortical laminae with calibrated functional MRI. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 15115-15120. PMID: 23980158, PMCID: PMC3773779, DOI: 10.1073/pnas.1307154110.Peer-Reviewed Original ResearchConceptsCerebral blood volumeLocal field potentialsMultiunit activitySomatosensory cortexCortical laminaeBlood oxygenation level-dependent (BOLD) signalRat somatosensory cortexLevel-dependent signalNeurometabolic couplingCerebral cortexSuperficial laminaeCBF changesDeep laminaeMagnetic resonance imaging dataBlood flowQuantitative neuroimagingBlood volumeFunctional MRISensory stimulationBOLD signalOxidative metabolismCortexLayer-specific responsesMetabolic measurementsField potentials
2011
Role of Ongoing, Intrinsic Activity of Neuronal Populations for Quantitative Neuroimaging of Functional Magnetic Resonance Imaging–Based Networks
Hyder F, Herman P, Sanganahalli BG, Coman D, Blumenfeld H, Rothman DL. Role of Ongoing, Intrinsic Activity of Neuronal Populations for Quantitative Neuroimaging of Functional Magnetic Resonance Imaging–Based Networks. Brain Connectivity 2011, 1: 185-193. PMID: 22433047, PMCID: PMC3621320, DOI: 10.1089/brain.2011.0032.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingEnergy/activityMagnetic resonance imagingBOLD signalNeuronal activityQuantitative neuroimagingNeuronal populationsResonance imagingBaseline BOLD signalsTotal neuronal activityBlood oxygenation level-dependent (BOLD) signalLevel-dependent signalResting-state fMRI experimentsAnimal modelsFMRI experimentMagnetic resonance spectroscopy measurementsBrain networksBaselineNeuroimagingPrimary objectiveImagingIntrinsic activityActivityPopulation
2010
Neurovascular and Neurometabolic Couplings in Dynamic Calibrated fMRI: Transient Oxidative Neuroenergetics for Block-Design and Event-Related Paradigms
Hyder F, Sanganahalli BG, Herman P, Coman D, Maandag NJ, Behar KL, Blumenfeld H, Rothman DL. Neurovascular and Neurometabolic Couplings in Dynamic Calibrated fMRI: Transient Oxidative Neuroenergetics for Block-Design and Event-Related Paradigms. Frontiers In Neuroenergetics 2010, 2: 18. PMID: 20838476, PMCID: PMC2936934, DOI: 10.3389/fnene.2010.00018.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingCerebral blood flowMulti-unit activityLocal field potentialsNeurometabolic couplingQuantitative functional magnetic resonance imagingBOLD signalCerebral metabolic rateNeural activityBlood oxygenation level-dependent (BOLD) contrastMagnetic resonance imagingMapping brain activityLevel-dependent contrastBlood flowMUA recordingsNeurophysiological parametersAnimal studiesResonance imagingBrain functionTissue poolsEvent-related paradigmField potentialsBrain activityNeural activity recordingActivity recordings
2007
Negative BOLD with Large Increases in Neuronal Activity
Schridde U, Khubchandani M, Motelow JE, Sanganahalli BG, Hyder F, Blumenfeld H. Negative BOLD with Large Increases in Neuronal Activity. Cerebral Cortex 2007, 18: 1814-1827. PMID: 18063563, PMCID: PMC2790390, DOI: 10.1093/cercor/bhm208.Peer-Reviewed Original ResearchConceptsCerebral blood flowCerebral blood volumeFunctional magnetic resonance imagingNegative BOLD signalsNeuronal activityBOLD signalLevel-dependent functional magnetic resonance imagingBlood oxygen level-dependent functional magnetic resonance imagingBOLD functional magnetic resonance imagingCerebral metabolic ratePositive BOLD signalMagnetic resonance imagingBlood flowNegative BOLDBlood volumeResonance imagingBrain regionsPathological conditionsNeuronal recordingsBrain activityFMRI signalsOxygen consumptionMetabolic rateMetabolic activitySeizures