Investigating Polycystin‐2‐mediated mitophagy as a stress response through its role in NAFLD
Brill A, Kuo I, Ehrlich B. Investigating Polycystin‐2‐mediated mitophagy as a stress response through its role in NAFLD. The FASEB Journal 2020, 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.04144.Peer-Reviewed Original ResearchPolycystin-2PTEN-induced putative kinase 1Mitochondrial functionStress response proteinsPutative kinase 1Endoplasmic reticulum membraneGeneral autophagyAthanogene 2Response proteinsDefective autophagyKinase 1Stress responseBAG2 expressionMitophagyReticulum membraneAberrant dysregulationAutophagyBcl-2High-fat dietSpecific roleMurine liverHaploinsufficient miceProteinBAG2Ca 2