2024
Advances in predicting breast cancer driver mutations: Tools for precision oncology (Review)
Hao W, Rajendran B, Cui T, Sun J, Zhao Y, Palaniyandi T, Selvam M. Advances in predicting breast cancer driver mutations: Tools for precision oncology (Review). International Journal Of Molecular Medicine 2024, 55: 6. PMID: 39450552, PMCID: PMC11537269, DOI: 10.3892/ijmm.2024.5447.Peer-Reviewed Original ResearchConceptsDisease-free survivalBreast cancerPrecision medicine approachAvailability of high-throughput sequencingPrecision oncologyTherapeutic optionsDriver mutationsDisease-free survival of patientsCancer driver gene identificationDriver gene identificationMedicine approachHigh-throughput sequencingSurvival of patientsTargeted therapeutic optionsFraction of patientsCancer driver mutationsTargeted therapeutic approachesBreast cancer treatmentIdentification of driver mutationsBreast cancer mutationsModern era of medicineCancer-specific biomarkersGene identificationCancer DatabaseCancer mutations
2017
Characterization of potential driver mutations involved in human breast cancer by computational approaches
Rajendran B, Deng C. Characterization of potential driver mutations involved in human breast cancer by computational approaches. Oncotarget 2017, 5: 50252-50272. PMID: 28477017, PMCID: PMC5564847, DOI: 10.18632/oncotarget.17225.Peer-Reviewed Original ResearchConceptsBreast cancerHuman breast cancerBreast cancer initiationForms of cancerPotential driver mutationsLethal cancersBreast tumorigenesisCancerDriver mutationsTumor initiationGenetic mutationsCancer initiationDriver genesPathway analysisProgressionMutation genesCellular regulatory pathwaysCandidate driversRegulatory pathwaysMetastasisCancer driversInitiation