Corticotrophin-Releasing Hormone Type 1 Receptor Gene ( CRHR1 ) Variants Predict Posttraumatic Stress Disorder Onset and Course in Pediatric Injury Patients
Amstadter A, Nugent N, Yang B, Miller A, Siburian R, Moorjani P, Haddad S, Basu A, Fagerness J, Saxe G, Smoller J, Koenen K. Corticotrophin-Releasing Hormone Type 1 Receptor Gene ( CRHR1 ) Variants Predict Posttraumatic Stress Disorder Onset and Course in Pediatric Injury Patients. Disease Markers 2011, 30: 89-99. DOI: 10.1155/2011/928497.Peer-Reviewed Original ResearchPosttraumatic stress disorderPediatric injury patientsTraumatic event exposureInjury patientsSingle nucleotide polymorphismsPosttraumatic stress disorder onsetAcute PTSD symptomsEvent exposureTrajectory of symptomsReceptor gene variantsLongitudinal latent growth curve analysesAcute symptomsProspective studyPresent studySpecific molecular variantsDisorder onsetAcute aftermathFuture replication studiesPosttraumatic stress symptomsTraumatic life eventsSymptomsStress disorderAnxiety disordersPTSD symptomsSymptom levels