2024
Botulinum Toxin Treatment of Psoriasis—A Comprehensive Review
Ghaseminejad-Bandpey A, Etemadmoghadam S, Jabbari B. Botulinum Toxin Treatment of Psoriasis—A Comprehensive Review. Toxins 2024, 16: 449. PMID: 39453225, PMCID: PMC11510791, DOI: 10.3390/toxins16100449.Peer-Reviewed Original ResearchConceptsOpen-label studyClinical trialsAnimal studiesPlacebo-controlled studyInjection of botulinum toxinPsoriatic skin lesionsLevels of interleukinsBotulinum toxin injectionOpen-labelDouble-blindBotulinum toxin treatmentCase reportInflammatory cellsPsoriatic plaquesSkin lesionsSmall dosesToxin injectionToxin treatmentLiterature searchBotulinum toxinRelevant articlesPsoriasisInterleukinHuman dataDose
2023
Botulinum Toxin Treatment for Cancer-Related Disorders: A Systematic Review
Safarpour D, Jabbari B. Botulinum Toxin Treatment for Cancer-Related Disorders: A Systematic Review. Toxins 2023, 15: 689. PMID: 38133193, PMCID: PMC10748363, DOI: 10.3390/toxins15120689.Peer-Reviewed Original ResearchConceptsBoNT injectionsFacial sweatingCancer-related disordersParotid regionSystematic reviewComplication of parotidectomySevere jaw painBotulinum toxin treatmentParotid gland surgeryBotulinum neurotoxin therapyCessation of painSerious side effectsSite of surgeryBoNT effectsGustatory hyperhidrosisJaw painNeurotoxin therapySteroid injectionLocal resectionEsophageal strictureSurgical approachEsophageal cancerLocal injectionSaline injectionToxin treatment
2018
Botulinum Toxin in Restless Legs Syndrome—A Randomized Double-Blind Placebo-Controlled Crossover Study
Mittal SO, Machado D, Richardson D, Dubey D, Jabbari B. Botulinum Toxin in Restless Legs Syndrome—A Randomized Double-Blind Placebo-Controlled Crossover Study. Toxins 2018, 10: 401. PMID: 30274305, PMCID: PMC6215171, DOI: 10.3390/toxins10100401.Peer-Reviewed Original ResearchConceptsRestless legs syndromePain scoresCrossover studyLegs syndromePlacebo-controlled crossover studyDouble-blind placeboPatient Global ImpressionVisual analog scalePrevious smaller studiesCommon movement disorderQuality of lifeIncobotulinumtoxin APlacebo groupRLS symptomsAnalog scaleGlobal ImpressionOnabotulinumtoxin ALife QuestionnaireTibialis anteriorBotulinum toxinNormal salineMovement disordersRLS scoresSmall studyFemoris muscleBotulinum toxin in essential hand tremor - A randomized double-blind placebo-controlled study with customized injection approach
Mittal SO, Machado D, Richardson D, Dubey D, Jabbari B. Botulinum toxin in essential hand tremor - A randomized double-blind placebo-controlled study with customized injection approach. Parkinsonism & Related Disorders 2018, 56: 65-69. PMID: 29929813, DOI: 10.1016/j.parkreldis.2018.06.019.Peer-Reviewed Original ResearchConceptsHand weaknessEssential hand tremorDouble-blind placebo-controlled studyEssential tremorAdministration of onabotulinumtoxinASevere hand weaknessPlacebo-controlled studyClinical rating scoresHand tremorRating scoresParkinson's disease tremorIncobotulinumtoxinA injectionsCrossover trialPatients' perceptionsBotulinum toxinTreatment efficacyClinical practiceHand strengthForearm musclesTremor severityClinical scalesTremorWeeksTreatmentInjectionBotulinum toxin treatment of pain syndromes –an evidence based review
Safarpour Y, Jabbari B. Botulinum toxin treatment of pain syndromes –an evidence based review. Toxicon 2018, 147: 120-128. PMID: 29409817, DOI: 10.1016/j.toxicon.2018.01.017.Peer-Reviewed Original ResearchConceptsLevel B evidencePain syndromeLevel of evidencePelvic painB evidenceMale pelvic pain syndromeChronic low back painTraumatic spinal cord injuryEfficacy of BoNTFemale pelvic painMale pelvic painVastus lateralis imbalanceMyofascial pain syndromePelvic pain syndromePost-herpetic neuralgiaAnterior knee painBotulinum toxin treatmentPainful knee osteoarthritisPost-operative painDifferent pain syndromesLow back painSpinal cord injuryCarpal tunnel syndromeTotal knee arthroplastyRole of BoNT
2017
The nature, consequences, and management of neurological disorders in chronic kidney disease
Jabbari B, Vaziri ND. The nature, consequences, and management of neurological disorders in chronic kidney disease. Hemodialysis International 2017, 22: 150-160. PMID: 28799704, DOI: 10.1111/hdi.12587.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseNeurological disordersNeurological symptomsKidney diseaseImpaired blood-brain barrierDiffuse white matter diseasePeripheral neurological symptomsRestless legs syndromeCentral neurological symptomsBlood-brain barrierWhite matter diseaseCentral nervous systemReflex myoclonusNeurological complicationsPeripheral neuropathyBrain edemaCortical myoclonusHemodynamic disordersLegs syndromePeripheral originBasal gangliaBrain barrierSubcortical lesionsMovement disordersSubcortical pathologyBotulinum Toxin in Parkinson Disease Tremor A Randomized, Double-Blind, Placebo-Controlled Study With a Customized Injection Approach
Mittal SO, Machado D, Richardson D, Dubey D, Jabbari B. Botulinum Toxin in Parkinson Disease Tremor A Randomized, Double-Blind, Placebo-Controlled Study With a Customized Injection Approach. Mayo Clinic Proceedings 2017, 92: 1359-1367. PMID: 28789780, DOI: 10.1016/j.mayocp.2017.06.010.Peer-Reviewed Original ResearchConceptsDisease Rating ScaleHand weaknessPatients' perceptionsUnified Parkinson's Disease Rating ScaleParkinson's Disease Rating ScaleAdministration of onabotulinumtoxinASevere hand weaknessUse of onabotulinumtoxinAPatient Global ImpressionClinical rating scoresTreatment of tremorParkinson's disease tremorIncobotulinumtoxinA injectionsCrossover trialGlobal ImpressionGrip strengthRest tremorBotulinum toxinPD tremorPostural tremorTreatment efficacyClinical practiceSignificant improvementEssential tremorHand strength
2016
Abobotulinum Toxin A in the Treatment of Chronic Low Back Pain
Machado D, Kumar A, Jabbari B. Abobotulinum Toxin A in the Treatment of Chronic Low Back Pain. Toxins 2016, 8: 374. PMID: 27983689, PMCID: PMC5198568, DOI: 10.3390/toxins8120374.Peer-Reviewed Original ResearchConceptsChronic low back painLow back painVisual analog scaleOswestry Low Back Pain Disability QuestionnaireAbobotulinum toxin ABack painQuality of lifeToxin APain Disability QuestionnairePatient Global ImpressionLevel of painPrimary outcome measureProportion of respondersStrong analgesic effectAbobotulinum toxinOswestry scorePlacebo groupAnalgesic effectDisability QuestionnaireMore patientsStudy cohortAnalog scaleGlobal ImpressionMultifactorial pathophysiologyPatients' perceptionsEffective Treatment of Paroxysmal Nonkinesigenic Dyskinesia With Oxcarbazepine
Kumar A, Szekely A, Jabbari B. Effective Treatment of Paroxysmal Nonkinesigenic Dyskinesia With Oxcarbazepine. Clinical Neuropharmacology 2016, 39: 201-205. PMID: 27046658, DOI: 10.1097/wnf.0000000000000149.Peer-Reviewed Original ResearchConceptsParoxysmal nonkinesigenic dyskinesiaRare chronic disorderOutcome of treatmentSeverity of episodesAvailable therapiesChronic disordersClinical trialsInvoluntary movementsEffective treatmentOxcarbazepinePharmaceutical agentsDyskinesiaPatientsTreatmentDisordersTherapyDebilitatingDiseaseTrialsSeverityBrain metastasis in breast cancer: a comprehensive literature review
Rostami R, Mittal S, Rostami P, Tavassoli F, Jabbari B. Brain metastasis in breast cancer: a comprehensive literature review. Journal Of Neuro-Oncology 2016, 127: 407-414. PMID: 26909695, DOI: 10.1007/s11060-016-2075-3.Peer-Reviewed Original ResearchConceptsHuman epithelial growth factor receptor 2Brain metastasesBreast cancerEstrogen receptorMultiple metastasesPositive tumorsProgesterone receptorLonger survivalNovel therapiesWhole-brain radiation therapyBrain metastasis diagnosisAxillary node metastasesBrain radiation therapyGrowth factor receptor 2PR-positive tumorsPrimary breast cancerExtra-cranial metastasesMedian time intervalHER2-positive tumorsBlood-brain barrierFuture therapeutic targetsFactor receptor 2Hormonal therapyMost patientsSurgical resectionBotulinum Toxin Treatment in Neurology
Jabbari B. Botulinum Toxin Treatment in Neurology. Seminars In Neurology 2016, 36: 003-004. PMID: 26866489, DOI: 10.1055/s-0036-1571849.Peer-Reviewed Original ResearchBotulinum Toxin Treatment of Spasticity in Adults and Children
Moeini-Naghani I, Hashemi-Zonouz T, Jabbari B. Botulinum Toxin Treatment of Spasticity in Adults and Children. Seminars In Neurology 2016, 36: 064-072. PMID: 26866498, DOI: 10.1055/s-0036-1571847.Peer-Reviewed Original ResearchConceptsCerebral palsyPlacebo-controlled clinical trialDoses of BoNTSpasticity of childrenBotulinum toxin treatmentAdult spasticityTherapeutics subcommitteeBoNT treatmentPharmacologic treatmentFrequent symptomsMultiple sclerosisSpinal traumaClinical trialsToxin treatmentSpasticityAmerican AcademyPalsyBotulinum neurotoxinTreatmentChildrenWorld literatureEfficacyAdultsSclerosisPathophysiologyBotulinum Toxin Treatment of Neuropathic Pain
Mittal SO, Safarpour D, Jabbari B. Botulinum Toxin Treatment of Neuropathic Pain. Seminars In Neurology 2016, 36: 073-083. PMID: 26866499, DOI: 10.1055/s-0036-1571953.Peer-Reviewed Original ResearchConceptsNeuropathic painBoNT treatmentComplex regional pain syndromeBotulinum toxin treatmentPainful diabetic neuropathyRegional pain syndromeCarpal tunnel syndromePhantom limb painEvidence-based statementsForm of painTechnique of injectionPosttraumatic neuralgiaAnalgesic medicationPain syndromePostherpetic neuralgiaDiabetic neuropathyOccipital neuralgiaLevel of efficacyLimb painTrigeminal neuralgiaTunnel syndromeClinical trialsToxin treatmentPainNeuralgiaIncobotulinum Toxin-A Improves Post-Surgical and Post-Radiation Pain in Cancer Patients
Rostami R, Mittal SO, Radmand R, Jabbari B. Incobotulinum Toxin-A Improves Post-Surgical and Post-Radiation Pain in Cancer Patients. Toxins 2016, 8: 22. PMID: 26771640, PMCID: PMC4728544, DOI: 10.3390/toxins8010022.Peer-Reviewed Original ResearchConceptsVisual analog scaleCancer patientsGlobal ImpressionSite of radiationPoor general conditionPatient Global ImpressionLocation of painIncobotulinum toxin AFocal painAnalgesic medicationPain controlAnalog scaleSkin reactionsToxin ALocal cancerPatientsSignificant improvementPainSurgeryChange ScaleResearch protocolSignificant satisfactionGeneral conditionMedicationsFollow
2015
Treatment of Chronic Migraine with Focus on Botulinum Neurotoxins
Schaefer SM, Gottschalk CH, Jabbari B. Treatment of Chronic Migraine with Focus on Botulinum Neurotoxins. Toxins 2015, 7: 2615-2628. PMID: 26184313, PMCID: PMC4516932, DOI: 10.3390/toxins7072615.Peer-Reviewed Original ResearchConceptsChronic migraineBotulinum toxin injection therapyLarge healthcare costsBotulinum toxin therapyTreatment of migraineCommon neurological disorderToxin therapyInjection therapyPathophysiological mechanismsMigraine pathophysiologyHealthcare costsMigraineNeurological disordersAnimal dataBotulinum neurotoxinTherapyTreatmentInjection techniqueCurrent understandingMedicationsPathophysiology
2014
Brain metastasis from ovarian cancer: a systematic review
Pakneshan S, Safarpour D, Tavassoli F, Jabbari B. Brain metastasis from ovarian cancer: a systematic review. Journal Of Neuro-Oncology 2014, 119: 1-6. PMID: 24789253, DOI: 10.1007/s11060-014-1447-9.Peer-Reviewed Original ResearchConceptsBrain metastasesOvarian cancerMultimodality treatmentRare causeBrain metastasis diagnosisHigher KPS scoreProgressive neurologic disabilityMajority of patientsMultiple brain lesionsSystematic literature searchOvarian cancer diagnosisLower KPSParaclinical informationKPS scoreExtracranial metastasesMedian survivalNeurologic disabilityOlder patientsSurgical resectionFavorable prognosisLymph nodesMedian ageMedical therapyVisual disturbancesCommon symptoms
2013
Primary dystonias and genetic disorders with dystonia as clinical feature of the disease
Moghimi N, Jabbari B, Szekely AM. Primary dystonias and genetic disorders with dystonia as clinical feature of the disease. European Journal Of Paediatric Neurology 2013, 18: 79-105. PMID: 23911094, DOI: 10.1016/j.ejpn.2013.05.015.Peer-Reviewed Original ResearchConceptsPrimary dystoniaClinical featuresSustained muscle contractionsCharacteristic clinical featuresClinical entityAbnormal postureMovement disordersDystoniaClinical practiceClinical phenomenologyAdvances of geneticsGenetic syndromesMuscle contractionRepetitive movementsUnderlining etiologiesDisordersCommon formMonogenic disordersGenetic disordersMolecular underpinningsDetailed searchMendelian disordersComplex casesLarge groupSyndromeIntramedullary metastasis in breast cancer – A comprehensive literature review
Rostami R, Safarpour D, Tavassoli FA, Jabbari B. Intramedullary metastasis in breast cancer – A comprehensive literature review. Journal Of The Neurological Sciences 2013, 332: 16-20. PMID: 23778028, DOI: 10.1016/j.jns.2013.05.032.Peer-Reviewed Original ResearchConceptsCerebrospinal fluidIntramedullary metastasisBrain metastasesTrue incidenceTreatment strategiesBreast cancerMedline/Pub MedBrown-Sequard syndromeConcurrent brain metastasisThoracic cord lesionsBreast cancer metastasisMagnetic resonance imagingBreast cancer diagnosisBladder dysfunctionBreast metastasisCord lesionsThoracic cordBetter prognosisClinical symptomsLung metastasesUnfavorable prognosisLonger survivalSpinal cordTumor markersMetastasisSialorrhea: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins
Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins. Toxins 2013, 5: 1010-1031. PMID: 23698357, PMCID: PMC3709276, DOI: 10.3390/toxins5051010.Peer-Reviewed Original ResearchConceptsBotulinum toxinSide effectsAdministration of BoNTLevel B evidencePlacebo-controlled studyCurrent medical managementTroublesome side effectsLevel of evidenceOral agentsCerebral palsyClinical featuresExcessive droolingMedical managementTopical agentsB evidenceBlinded studyMedical treatmentAmerican AcademyClinical notesDrug efficacyNeurodegenerative disordersClinical pointB levelsSalivary glandsType BHyperhidrosis: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins
Lakraj AA, Moghimi N, Jabbari B. Hyperhidrosis: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins. Toxins 2013, 5: 821-840. PMID: 23612753, PMCID: PMC3705293, DOI: 10.3390/toxins5040821.Peer-Reviewed Original ResearchConceptsClass II studiesII studyAxillary hyperhidrosisPalmar hyperhidrosisComparator studiesBotulinum toxinClass IEvidence level BLevel of evidenceClass III studiesOral agentsIII studyClinical featuresTopical agentsComparable efficacyLong lasting effectInjection sessionsBlinded studyAmerican AcademyDrug efficacyClass IIHyperhidrosisEfficacyWorld literatureToxin