2018
Botulinum Toxin in Restless Legs Syndrome—A Randomized Double-Blind Placebo-Controlled Crossover Study
Mittal SO, Machado D, Richardson D, Dubey D, Jabbari B. Botulinum Toxin in Restless Legs Syndrome—A Randomized Double-Blind Placebo-Controlled Crossover Study. Toxins 2018, 10: 401. PMID: 30274305, PMCID: PMC6215171, DOI: 10.3390/toxins10100401.Peer-Reviewed Original ResearchConceptsRestless legs syndromePain scoresCrossover studyLegs syndromePlacebo-controlled crossover studyDouble-blind placeboPatient Global ImpressionVisual analog scalePrevious smaller studiesCommon movement disorderQuality of lifeIncobotulinumtoxin APlacebo groupRLS symptomsAnalog scaleGlobal ImpressionOnabotulinumtoxin ALife QuestionnaireTibialis anteriorBotulinum toxinNormal salineMovement disordersRLS scoresSmall studyFemoris muscleBotulinum toxin in essential hand tremor - A randomized double-blind placebo-controlled study with customized injection approach
Mittal SO, Machado D, Richardson D, Dubey D, Jabbari B. Botulinum toxin in essential hand tremor - A randomized double-blind placebo-controlled study with customized injection approach. Parkinsonism & Related Disorders 2018, 56: 65-69. PMID: 29929813, DOI: 10.1016/j.parkreldis.2018.06.019.Peer-Reviewed Original ResearchConceptsHand weaknessEssential hand tremorDouble-blind placebo-controlled studyEssential tremorAdministration of onabotulinumtoxinASevere hand weaknessPlacebo-controlled studyClinical rating scoresHand tremorRating scoresParkinson's disease tremorIncobotulinumtoxinA injectionsCrossover trialPatients' perceptionsBotulinum toxinTreatment efficacyClinical practiceHand strengthForearm musclesTremor severityClinical scalesTremorWeeksTreatmentInjection
2017
Botulinum Toxin in Parkinson Disease Tremor A Randomized, Double-Blind, Placebo-Controlled Study With a Customized Injection Approach
Mittal SO, Machado D, Richardson D, Dubey D, Jabbari B. Botulinum Toxin in Parkinson Disease Tremor A Randomized, Double-Blind, Placebo-Controlled Study With a Customized Injection Approach. Mayo Clinic Proceedings 2017, 92: 1359-1367. PMID: 28789780, DOI: 10.1016/j.mayocp.2017.06.010.Peer-Reviewed Original ResearchConceptsDisease Rating ScaleHand weaknessPatients' perceptionsUnified Parkinson's Disease Rating ScaleParkinson's Disease Rating ScaleAdministration of onabotulinumtoxinASevere hand weaknessUse of onabotulinumtoxinAPatient Global ImpressionClinical rating scoresTreatment of tremorParkinson's disease tremorIncobotulinumtoxinA injectionsCrossover trialGlobal ImpressionGrip strengthRest tremorBotulinum toxinPD tremorPostural tremorTreatment efficacyClinical practiceSignificant improvementEssential tremorHand strength
2016
Abobotulinum Toxin A in the Treatment of Chronic Low Back Pain
Machado D, Kumar A, Jabbari B. Abobotulinum Toxin A in the Treatment of Chronic Low Back Pain. Toxins 2016, 8: 374. PMID: 27983689, PMCID: PMC5198568, DOI: 10.3390/toxins8120374.Peer-Reviewed Original ResearchConceptsChronic low back painLow back painVisual analog scaleOswestry Low Back Pain Disability QuestionnaireAbobotulinum toxin ABack painQuality of lifeToxin APain Disability QuestionnairePatient Global ImpressionLevel of painPrimary outcome measureProportion of respondersStrong analgesic effectAbobotulinum toxinOswestry scorePlacebo groupAnalgesic effectDisability QuestionnaireMore patientsStudy cohortAnalog scaleGlobal ImpressionMultifactorial pathophysiologyPatients' perceptions
2011
Treatment of Refractory Pain with Botulinum Toxins—An Evidence-Based Review
Jabbari B, Machado D. Treatment of Refractory Pain with Botulinum Toxins—An Evidence-Based Review. Pain Medicine 2011, 12: 1594-1606. PMID: 21958302, DOI: 10.1111/j.1526-4637.2011.01245.x.Peer-Reviewed Original ResearchConceptsPost-operative painRefractory painBotulinum toxinChronic low back painChronic lateral epicondylitisClass II articlesLevel B evidenceLevel C evidencePost-traumatic neuralgiaVastus lateralis imbalanceMyofascial pain syndromePlacebo-controlled studyPost-herpetic neuralgiaAnterior knee painPainful knee osteoarthritisChronic daily headacheLow back painTotal knee arthroplastyEvidence-based reviewEvidence-based dataSphincter spasmKnee painPain syndromePelvic painPiriformis syndrome
2010
Botulinum Toxin A for Treatment of Allodynia of Complex Regional Pain Syndrome: A Pilot Study
Safarpour D, Salardini A, Richardson D, Jabbari B. Botulinum Toxin A for Treatment of Allodynia of Complex Regional Pain Syndrome: A Pilot Study. Pain Medicine 2010, 11: 1411-1414. PMID: 20609130, DOI: 10.1111/j.1526-4637.2010.00897.x.Peer-Reviewed Original ResearchConceptsComplex regional pain syndromeRegional pain syndromeBotulinum toxin APain syndromeToxin AOpen-label protocolPain Impact QuestionnairePlacebo-controlled protocolTreatment of allodyniaBrief Pain InventoryMcGill Pain QuestionnaireGlobal satisfaction scaleAllodynic areaAllodynic skinPain InventoryPain QuestionnaireImpact QuestionnaireSubcutaneous administrationPatientsSatisfaction ScaleAllodyniaPilot studySyndromeBoNTTreatment
2009
Botulinum Neurotoxin-A for Treatment of Refractory Neck Pain: A Randomized, Double-Blind Study
Miller D, Richardson D, Eisa M, Bajwa RJ, Jabbari B. Botulinum Neurotoxin-A for Treatment of Refractory Neck Pain: A Randomized, Double-Blind Study. Pain Medicine 2009, 10: 1012-1017. PMID: 19594841, DOI: 10.1111/j.1526-4637.2009.00658.x.Peer-Reviewed Original ResearchConceptsVisual analog scaleRefractory neck painNeck painExcellent respondersPrimary outcomeMean visual analog scaleAdministration of BoNTEfficacy of BoNTUnits of BoNTChronic neck painPlacebo-controlled studyDouble-blind studyImprovement of ADLBotulinum neurotoxinPlacebo groupAnalgesic effectBotox groupFrequency questionnaireSecondary outcomesPain intensityPain localizationPain QuestionnaireAnalog scaleBlinded studyAnimal studies