Sialorrhea: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins
Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins. Toxins 2013, 5: 1010-1031. PMID: 23698357, PMCID: PMC3709276, DOI: 10.3390/toxins5051010.Peer-Reviewed Original ResearchConceptsBotulinum toxinSide effectsAdministration of BoNTLevel B evidencePlacebo-controlled studyCurrent medical managementTroublesome side effectsLevel of evidenceOral agentsCerebral palsyClinical featuresExcessive droolingMedical managementTopical agentsB evidenceBlinded studyMedical treatmentAmerican AcademyClinical notesDrug efficacyNeurodegenerative disordersClinical pointB levelsSalivary glandsType BHyperhidrosis: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins
Lakraj AA, Moghimi N, Jabbari B. Hyperhidrosis: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins. Toxins 2013, 5: 821-840. PMID: 23612753, PMCID: PMC3705293, DOI: 10.3390/toxins5040821.Peer-Reviewed Original ResearchConceptsClass II studiesII studyAxillary hyperhidrosisPalmar hyperhidrosisComparator studiesBotulinum toxinClass IEvidence level BLevel of evidenceClass III studiesOral agentsIII studyClinical featuresTopical agentsComparable efficacyLong lasting effectInjection sessionsBlinded studyAmerican AcademyDrug efficacyClass IIHyperhidrosisEfficacyWorld literatureToxin