Botulinum Toxin in Parkinson Disease Tremor A Randomized, Double-Blind, Placebo-Controlled Study With a Customized Injection Approach
Mittal SO, Machado D, Richardson D, Dubey D, Jabbari B. Botulinum Toxin in Parkinson Disease Tremor A Randomized, Double-Blind, Placebo-Controlled Study With a Customized Injection Approach. Mayo Clinic Proceedings 2017, 92: 1359-1367. PMID: 28789780, DOI: 10.1016/j.mayocp.2017.06.010.Peer-Reviewed Original ResearchConceptsDisease Rating ScaleHand weaknessPatients' perceptionsUnified Parkinson's Disease Rating ScaleParkinson's Disease Rating ScaleAdministration of onabotulinumtoxinASevere hand weaknessUse of onabotulinumtoxinAPatient Global ImpressionClinical rating scoresTreatment of tremorParkinson's disease tremorIncobotulinumtoxinA injectionsCrossover trialGlobal ImpressionGrip strengthRest tremorBotulinum toxinPD tremorPostural tremorTreatment efficacyClinical practiceSignificant improvementEssential tremorHand strength