Exercise-Training in Young Drosophila melanogaster Reduces Age-Related Decline in Mobility and Cardiac Performance
Piazza N, Gosangi B, Devilla S, Arking R, Wessells R. Exercise-Training in Young Drosophila melanogaster Reduces Age-Related Decline in Mobility and Cardiac Performance. PLOS ONE 2009, 4: e5886. PMID: 19517023, PMCID: PMC2691613, DOI: 10.1371/journal.pone.0005886.Peer-Reviewed Original ResearchConceptsInvertebrate genetic model systemGenetic model systemUnbiased genetic screenGenetic screenDrosophila melanogasterGenetic basisYoung fliesMitochondrial efficiencyAmount of proteinFliesExercise training modelPhysiological responsesModel systemGenetic therapiesMelanogasterMechanized platformNegative geotaxisLociProteinPhenotypeResponseGreat promiseLipidsAge-related declineMajor source