Decoding Neural Circuits that Control Compulsive Sucrose Seeking
Nieh E, Matthews G, Allsop S, Presbrey K, Leppla C, Wichmann R, Neve R, Wildes C, Tye K. Decoding Neural Circuits that Control Compulsive Sucrose Seeking. Cell 2015, 160: 528-541. PMID: 25635460, PMCID: PMC4312417, DOI: 10.1016/j.cell.2015.01.003.Peer-Reviewed Original ResearchConceptsVentral tegmental areaVentral tegmental area dopamineNeural circuitsReward-predictive cuesFeeding-related behaviorsSucrose seekingReward omissionReward processingReward availabilityTegmental areaHungry miceGABA neuronsLH neuronsGABAergic projectionsDopamineRewardLearning actionsInhibitory inputsNeuronsTherapeutic interventionsSeekingCuesDisordersGABAFood consumption