2004
Regulation of Interleukin-8 Expression in Human Endometrial Endothelial Cells: A Potential Mechanism for the Pathogenesis of Endometriosis
Luk J, Seval Y, Kayisli UA, Ulukus M, Ulukus CE, Arici A. Regulation of Interleukin-8 Expression in Human Endometrial Endothelial Cells: A Potential Mechanism for the Pathogenesis of Endometriosis. The Journal Of Clinical Endocrinology & Metabolism 2004, 90: 1805-1811. PMID: 15613411, DOI: 10.1210/jc.2004-1813.Peer-Reviewed Original ResearchConceptsHuman endometrial endothelial cellsIL-8 mRNAEndometrial endothelial cellsIL-8 expressionSex steroidsEndothelial cellsEutopic endometriumCultured human endometrial endothelial cellsIL-8 immunoreactivityEffects of estradiolEutopic endometrial tissuesPathogenesis of endometriosisInterleukin-8 expressionMenstrual cycle phaseEndothelium-specific markersEndometriosis implantsInflammatory basisCytokine levelsEndometriotic implantsInflammatory mediatorsChemokine expressionEndometrial tissueInflammatory aspectsIL-8EndometriosisThe effect of sex steriods on IL-8 and MCP-1 expression in human endometrial endothelial cells − The gatekeeper of human endometrium
Luk J, Seval Y, Kayisli U, Arici A. The effect of sex steriods on IL-8 and MCP-1 expression in human endometrial endothelial cells − The gatekeeper of human endometrium. Fertility And Sterility 2004, 82: s62. DOI: 10.1016/j.fertnstert.2004.07.158.Peer-Reviewed Original Research
1997
Potential Therapeutic Use of Cytokines in Gynaecology and Obstetrics
Bukulmez O, Arici A. Potential Therapeutic Use of Cytokines in Gynaecology and Obstetrics. BioDrugs 1997, 8: 193-204. PMID: 18020510, DOI: 10.2165/00063030-199708030-00005.Peer-Reviewed Original ResearchInterleukin-1Preterm laborInfection-associated preterm laborIL-1 receptor antagonistIL-8 levelsIntra-amniotic infectionLuteinising hormone levelsCytokine-based therapiesTumor necrosis factorCentral nervous systemPotential therapeutic useLeukemia inhibitory factorPreterm parturitionCervical ripeningCytokine levelsAnticytokine agentsIL-1raCervical maturationIL-6IL-8Receptor antagonistFollicular ruptureProlactin levelsRoutine clinical applicationHormone levels
1996
The peritoneal environment in endometriosis
Oral E, Olive D, Arici A. The peritoneal environment in endometriosis. Human Reproduction Update 1996, 2: 385-398. PMID: 15717438, DOI: 10.1093/humupd/2.5.385.Peer-Reviewed Original ResearchConceptsPeritoneal fluidPeritoneal environmentPF of womenEtiology of endometriosisMonocytes/macrophagesSpermatozoon-oocyte interactionEndometriotic implantsEndometrial fragmentsPeritoneal factorsPeritoneal endometriosisRetrograde menstruationIL-8MCP-1Postimplantation survivalChemoattractant cytokinesMast cellsEndometriosisImmune systemMesothelial cellsCytokinesGrowth factorOvum captureMacrophagesEtiologyCell typesModulation of the levels of interleukin-8 messenger ribonucleic acid and interleukin-8 protein synthesis in human endometrial stromal cells by transforming growth factor-beta 1
Arici A, MacDonald P, Casey M. Modulation of the levels of interleukin-8 messenger ribonucleic acid and interleukin-8 protein synthesis in human endometrial stromal cells by transforming growth factor-beta 1. The Journal Of Clinical Endocrinology & Metabolism 1996, 81: 3004-3009. PMID: 8768866, DOI: 10.1210/jcem.81.8.8768866.Peer-Reviewed Original ResearchConceptsIL-8 messenger ribonucleic acidEndometrial stromal cellsHuman endometrial stromal cellsMessenger ribonucleic acidIL-8TGF beta 1Stromal cellsChemotactic factorsInterleukin-8 messenger ribonucleic acidT-cell chemotactic factorBone marrow-derived cellsBeta 1Ovarian steroid secretionTGF beta 1 treatmentImmunoreactive IL-8Marrow-derived cellsEndometrium/deciduaInterleukin-8 gene expressionIL-8 geneParacrine-acting factorsOvulatory womenEndometrial decidualizationEndometrial stromaSteroid secretionLeukocyte populations
1993
Regulation of interleukin-8 gene expression in human endometrial cells in culture
Arici A, Head J, MacDonald P, Casey M. Regulation of interleukin-8 gene expression in human endometrial cells in culture. Molecular And Cellular Endocrinology 1993, 94: 195-204. PMID: 8224523, DOI: 10.1016/0303-7207(93)90168-j.Peer-Reviewed Original ResearchConceptsIL-8 mRNAEndometrial stromal cellsIL-1 alphaInterleukin-8 gene expressionEndometrial epithelial cellsStromal cellsEpithelial cellsIL-8 mRNA levelsImmunoreactive IL-8IL-8 gene expressionIL-8 gene transcriptionHuman endometrial cellsRecruitment of leukocytesIL-1 treatmentConcentration-dependent mannerIL-8Endometrial cellsTumor necrosisHuman endometriumGene expressionIL-1Glandular epitheliumSerum-free mediumSerum treatmentPresence of serum