1998
Chaperone Action in Folding Newly-Translated Cytosolic Proteins in Bacteria and Eukaryotes
Horwich A. Chaperone Action in Folding Newly-Translated Cytosolic Proteins in Bacteria and Eukaryotes. NATO ASI Series 1998, 41-63. DOI: 10.1007/978-3-642-51463-0_4.Peer-Reviewed Original ResearchNon-native conformationsNative statePrimary amino acid sequenceAmino acid sequenceNon-native statesSubstrate proteinsChaperone functionMolecular chaperonesBiogenesis stepsChaperone actionSpecialized proteinsCofactor bindingProtein foldingAction of nucleotidesPathway stepsMutational alterationsCytosolic proteinsAcid sequenceChaperonesSteric informationFolding processSuch hydrophobic interactionsProteinNative formEssential nature
1992
Chapter 26 Chaperonin-mediated protein folding
Horwich A, Caplan S, Wall J, Hartl F. Chapter 26 Chaperonin-mediated protein folding. New Comprehensive Biochemistry 1992, 22: 329-337. DOI: 10.1016/s0167-7306(08)60103-9.Peer-Reviewed Original ResearchFunction of GroELPrimary amino acid sequenceAmino acid sequenceLinear genomic DNAActive tertiary structureRelated organellesProtein foldingCentral dogmaAcid sequenceGenetic informationGenomic DNAQuaternary structureRNA messageSpontaneous foldingPrimary structureActive conformationDNA templateIntact cellsTertiary structureMolecular biologyPolypeptide chainAmino acidsBiological membranesProteinChaperonin
1985
A cDNA clone for the precursor of rat mitochondrial ornithine transcarbamylase: comparison of rat and human leader sequences and conservation of catalytic sites
Kraus J, Hodges P, Williamson C, Horwich A, Kalousek F, Williams K, Rosenberg L. A cDNA clone for the precursor of rat mitochondrial ornithine transcarbamylase: comparison of rat and human leader sequences and conservation of catalytic sites. Nucleic Acids Research 1985, 13: 943-952. PMID: 3839075, PMCID: PMC341044, DOI: 10.1093/nar/13.3.943.Peer-Reviewed Original ResearchConceptsAmino acid sequenceLeader sequenceAcid sequenceBasic residuesAmino-terminal leader sequenceE. coliComplete sequence homologyAmino acid residuesProtein sequence dataOrnithine transcarbamylaseCDNA clonesSequence dataDNA complementaryOrnithine transcarbamylasesSequence homologyEntire proteinHuman enzymeAcid residuesTranscarbamylasesComplementary DNAAmino acidsMessenger RNARat enzymeNucleotidesCatalytic site