Reduction of Blood Loss by Tranexamic Acid Following Total Hip and Knee Arthroplasty
Gianakos A, Hurley E, Haring R, Yoon R, Liporace F. Reduction of Blood Loss by Tranexamic Acid Following Total Hip and Knee Arthroplasty. JBJS Reviews 2018, 6: e1. PMID: 29738409, DOI: 10.2106/jbjs.rvw.17.00103.Peer-Reviewed Original ResearchConceptsIA TXATotal knee arthroplastyTotal blood lossTotal hip arthroplastyBlood lossTranexamic acidKnee arthroplastyIA administrationStandardized mean differenceHospital stayThromboembolic complicationsHip arthroplastyTXA administrationCohort studyDrain outputTotal hipIntra-articular tranexamic acidWeight-based protocolRetrospective cohort studyProspective cohort studySymptomatic thromboembolic complicationsOverall blood lossCochrane Library databasesTherapeutic Level IIIStandard dose