2018
Reduction of Blood Loss by Tranexamic Acid Following Total Hip and Knee Arthroplasty
Gianakos A, Hurley E, Haring R, Yoon R, Liporace F. Reduction of Blood Loss by Tranexamic Acid Following Total Hip and Knee Arthroplasty. JBJS Reviews 2018, 6: e1. PMID: 29738409, DOI: 10.2106/jbjs.rvw.17.00103.Peer-Reviewed Original ResearchConceptsIA TXATotal knee arthroplastyTotal blood lossTotal hip arthroplastyBlood lossTranexamic acidKnee arthroplastyIA administrationStandardized mean differenceHospital stayThromboembolic complicationsHip arthroplastyTXA administrationCohort studyDrain outputTotal hipIntra-articular tranexamic acidWeight-based protocolRetrospective cohort studyProspective cohort studySymptomatic thromboembolic complicationsOverall blood lossCochrane Library databasesTherapeutic Level IIIStandard doseDifferentiating Subchondral Insufficiency Fracture from Osteonecrosis May Help Avoid Unnecessary Total Hip Arthroplasty
Gianakos A, Moya-Angeler J, Haring R, Li A, Greditzer IV H, Lane J. Differentiating Subchondral Insufficiency Fracture from Osteonecrosis May Help Avoid Unnecessary Total Hip Arthroplasty. The Journal Of Hip Surgery 2018, 02: 047-053. DOI: 10.1055/s-0038-1646937.Peer-Reviewed Original ResearchSubchondral insufficiency fractureInsufficiency fracturesClinical featuresMagnetic resonance imaging (MRI) findingsLow signal intensity bandResonance Imaging FindingsX-ray findingsBone mineral densityTotal hip arthroplastyNonoperative managementRadiologic featuresImaging findingsMineral densityOperative procedureHip arthroplastyHigher oddsOsteonecrosisFemoral headMRI analysisBlinded radiologistsPatientsMRI
2016
The Efficacy of Bisphosphonates with Core Decompression and Mesenchymal Stem Cells Compared with Bisphosphonates Alone in the Treatment of Osteonecrosis of the Hip: A Retrospective Study
Gianakos A, Moya-Angeler J, Duggal S, Zambrana L, Fields K, Mintz D, Cornell C, Lane J. The Efficacy of Bisphosphonates with Core Decompression and Mesenchymal Stem Cells Compared with Bisphosphonates Alone in the Treatment of Osteonecrosis of the Hip: A Retrospective Study. HSS Journal ® 2016, 12: 137-144. PMID: 27385942, PMCID: PMC4916091, DOI: 10.1007/s11420-016-9487-7.Peer-Reviewed Original ResearchModified Harris Hip ScoreVisual analogue scoreTotal hip arthroplastyBisphosphonate therapyCore decompressionMesenchymal stem cellsFunctional outcomeTreatment groupsHip replacementFemoral headEfficacy of bisphosphonatesFicat stage IRadiologic outcome measuresHarris hip scoreYear of diagnosisTreatment of osteonecrosisFuture prospective studiesEarly-stage ONFHInclusion/exclusion criteriaStem cellsJoint preserving proceduresTotal hip replacementProgression of collapseFicat stageInstitution's registry
2015
Current concepts on osteonecrosis of the femoral head
Moya-Angeler J, Gianakos A, Villa J, Ni A, Lane J. Current concepts on osteonecrosis of the femoral head. World Journal Of Orthopedics 2015, 6: 590-601. PMID: 26396935, PMCID: PMC4573503, DOI: 10.5312/wjo.v6.i8.590.Peer-Reviewed Original ResearchMagnetic resonance imagingFemoral headCore decompressionFrog-leg lateral radiographsNatural historyFirst radiographic changeTrue natural historyLevel 1 evidenceOptimal treatment protocolTotal hip arthroplastyJoint preserving proceduresPre-collapse stageOsteonecrosis diagnosisPlain anteroposteriorSurgical treatmentAvascular necrosisPlain radiographsSclerotic changesTreatment optionsMinimal symptomsRadiographic changesTreatment modalitiesRisk factorsPharmacologic agentsSymptomatic stage