2020
Autologous osteochondral transplantation for osteochondral lesions of the talus: high rate of return to play in the athletic population
Seow D, Shimozono Y, Gianakos A, Chiarello E, Mercer N, Hurley E, Kennedy J. Autologous osteochondral transplantation for osteochondral lesions of the talus: high rate of return to play in the athletic population. Knee Surgery, Sports Traumatology, Arthroscopy 2020, 29: 1554-1561. PMID: 32856096, DOI: 10.1007/s00167-020-06216-w.Peer-Reviewed Original ResearchConceptsAutologous osteochondral transplantationQuality of evidenceOLT sizeRehabilitation protocolOsteochondral transplantationAthletic populationOsteochondral lesionsSystematic reviewPre-injury statusCochrane Library databasesLevel of evidencePredictors of returnSpecific eligibility criteriaHigh rateFixed-effects modelLevel IVSurgeons' protocolsLibrary databasesPRISMA guidelinesEligibility criteriaSubsequent rehabilitationIncrease ageMean timeSignificant correlationTransplantation
2018
Limited evidence for adipose‐derived stem cell therapy on the treatment of osteoarthritis
Hurley E, Yasui Y, Gianakos A, Seow D, Shimozono Y, Kerkhoffs G, Kennedy J. Limited evidence for adipose‐derived stem cell therapy on the treatment of osteoarthritis. Knee Surgery, Sports Traumatology, Arthroscopy 2018, 26: 3499-3507. PMID: 29713784, DOI: 10.1007/s00167-018-4955-x.Peer-Reviewed Original ResearchConceptsStromal vascular fractionPlatelet-rich plasmaTreatment of osteoarthritisClinical outcomesSystematic reviewForm of SVFUse of SVFAdipose-derived stem cell therapyEffects of ADSCsIncidence of swellingFavorable clinical outcomeLevel IV studiesCochrane Library databasesEffects of AdiposeDonor siteStem cell therapySVF injectionComplication rateBiological adjuvantsClinical studiesLevel IVExclusion criteriaLibrary databasesSide effectsAdipose tissue