2021
Tranexamic acid lowers transfusion requirements and hospital length of stay following revision total hip or knee arthroplasty
Gianakos A, Saad B, Haring R, Menken L, Elkattaway S, Liporace F, Yoon R. Tranexamic acid lowers transfusion requirements and hospital length of stay following revision total hip or knee arthroplasty. Patient Safety In Surgery 2021, 15: 21. PMID: 33975621, PMCID: PMC8111901, DOI: 10.1186/s13037-021-00295-5.Peer-Reviewed Original ResearchRevision TKA groupHospital stayRevision THA patientsTranexamic acidTKA groupBlood lossTransfusion rateThromboembolic complicationsTHA patientsJoint patientsTotal joint arthroplasty patientsBlood loss differenceRate of transfusionJoint arthroplasty patientsPrimary outcome measureRevision total hipTotal joint arthroplastyRevision joint replacementTransfusion requirementsTXA effectsTXA groupTXA patientsHospital lengthSystemic complicationsArthroplasty patients
2018
Reduction of Blood Loss by Tranexamic Acid Following Total Hip and Knee Arthroplasty
Gianakos A, Hurley E, Haring R, Yoon R, Liporace F. Reduction of Blood Loss by Tranexamic Acid Following Total Hip and Knee Arthroplasty. JBJS Reviews 2018, 6: e1. PMID: 29738409, DOI: 10.2106/jbjs.rvw.17.00103.Peer-Reviewed Original ResearchConceptsIA TXATotal knee arthroplastyTotal blood lossTotal hip arthroplastyBlood lossTranexamic acidKnee arthroplastyIA administrationStandardized mean differenceHospital stayThromboembolic complicationsHip arthroplastyTXA administrationCohort studyDrain outputTotal hipIntra-articular tranexamic acidWeight-based protocolRetrospective cohort studyProspective cohort studySymptomatic thromboembolic complicationsOverall blood lossCochrane Library databasesTherapeutic Level IIIStandard dose