2022
Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus—Does Sex Play a Role?
Gianakos A, Okedele O, Mulcahey M, Kerkhoffs G, Kennedy J. Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus—Does Sex Play a Role? The Journal Of Foot & Ankle Surgery 2022, 62: 96-101. PMID: 35753861, DOI: 10.1053/j.jfas.2022.05.005.Peer-Reviewed Original ResearchConceptsAutologous osteochondral transplantationFemale patientsOsteochondral lesionsMale patientsOsteochondral transplantationPotential gender-related differencesCartilage repair tissue (MOCART) scoreMean MOCART scoreAnkle Outcome ScoreMechanism of injuryChronic ankle instabilityTalar osteochondral lesionsGender-related differencesMean FAOSConsecutive patientsMagnetic resonance observationOutcome scoresFunctional outcomeMOCART scoreAnkle instabilityPatientsDemographic dataTissue scoresLesionsRehabilitation strategiesAutologous Osteochondral Transplantation for Osteochondral Lesions of the Talus: Does Gender Impact Outcomes?
Gianakos A, Okedele O, Flynn S, Mulcahey M, Kennedy J. Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus: Does Gender Impact Outcomes? Foot & Ankle Orthopaedics 2022, 7: 2473011421s00204. PMCID: PMC8795102, DOI: 10.1177/2473011421s00204.Peer-Reviewed Original ResearchAutologous osteochondral transplantationTalar osteochondral lesionsFemale patientsMale patientsChronic ankle instabilityOsteochondral lesionsOsteochondral transplantationAnkle instabilityKnee donor-site morbidityCartilage repair tissue (MOCART) scoreMean MOCART scoreLonger symptom durationAnkle Outcome ScoreDonor site morbidityMean FAOSFAOS scoresSymptom durationComplication rateConsecutive patientsMagnetic resonance observationOutcome scoresFunctional outcomeRevision surgeryMOCART scorePatients
2021
Outcomes After Arthroscopic Surgery for Anterior Impingement in the Ankle Joint in the General and Athletic Populations: Does Sex Play a Role?
Gianakos A, Ivander A, DiGiovanni C, Kennedy J. Outcomes After Arthroscopic Surgery for Anterior Impingement in the Ankle Joint in the General and Athletic Populations: Does Sex Play a Role? The American Journal Of Sports Medicine 2021, 49: 2834-2842. PMID: 33400547, DOI: 10.1177/0363546520980096.Peer-Reviewed Original ResearchConceptsAnterior ankle impingementAnkle impingementChronic ankle instabilityPatient sexAthletic populationSystematic reviewComplication rateMale patientsConcomitant pathologyFemale patientsAnkle sprainFunctional outcomeChondral injuriesAnkle instabilityAnkle Society (AOFAS) scaleAverage complication rateCommon concomitant pathologyAmerican Orthopaedic FootExcellent functional outcomeFoot Function IndexLow complication rateVisual analog scaleSystematic literature searchHigh rateAnteromedial impingement
2020
Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus: Does Gender Impact Outcomes?
Gianakos A, Okedele O, Flynn S, Kennedy J, DiGiovanni C. Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus: Does Gender Impact Outcomes? Foot & Ankle Orthopaedics 2020, 5: 2473011420s00227. PMCID: PMC8696434, DOI: 10.1177/2473011420s00227.Peer-Reviewed Original ResearchAutologous osteochondral transplantationFemale patientsTalar osteochondral lesionsOsteochondral lesionsMale patientsMOCART scoreOsteochondral transplantationKnee donor-site morbidityCartilage repair tissue (MOCART) scoreMean MOCART scoreLonger symptom durationAnkle Outcome ScoreDonor site morbidityMean FAOSSymptom durationFAOS scoresComplication rateConsecutive patientsMagnetic resonance observationOutcome scoresFunctional outcomeMean MRIRevision surgeryPatientsLesion sizeOutcomes Following Arthroscopy for Anterior Impingement in the Ankle Joint: Need for Gender as a Variable in Analysis
Gianakos A, Ivander A, DiGiovanni C, Kennedy J. Outcomes Following Arthroscopy for Anterior Impingement in the Ankle Joint: Need for Gender as a Variable in Analysis. Foot & Ankle Orthopaedics 2020, 5: 2473011420s00229. PMCID: PMC8704851, DOI: 10.1177/2473011420s00229.Peer-Reviewed Original ResearchAnterior ankle impingementComplication rateAnkle impingementFunctional outcomeSystematic reviewAverage complication rateCommon associated pathologyExcellent functional outcomeFunctional outcome scoresMajority of patientsLow complication rateSystematic literature searchAnteromedial impingementMeniscoid lesionsFFI scoresClinical outcomesMale patientsAnterior impingementArthroscopic interventionCochrane DatabaseOutcome scoresArthroscopic treatmentPatient satisfactionArthroscopic evaluationWorse outcomesTreatment for Acute Proximal Interphalangeal Joint Fractures and Fracture-Dislocations: A Systematic Review of the Literature
Gianakos A, Yingling J, Athens C, Barra A, Capo J. Treatment for Acute Proximal Interphalangeal Joint Fractures and Fracture-Dislocations: A Systematic Review of the Literature. Journal Of Hand And Microsurgery 2020, 12: s9-s15. PMID: 33335365, PMCID: PMC7735550, DOI: 10.1055/s-0040-1713323.Peer-Reviewed Original ResearchInterphalangeal joint fracturesDynamic external fixationVolar plate arthroplastyExternal fixationProximal interphalangeal joint fracturesLow complication rateCochrane Library databasesCommon hand injuriesLevel III studiesMore complex injuriesSeverity of injuryHemi-hamate arthroplastyJoint fracturesComplication rateIII studyPercutaneous pinningRecurrent painClosed reductionFracture dislocationFunctional outcomeHand injuriesInjury patternsInternal fixationTreatment optionsComplex injuriesEffect of Microfracture on Functional Outcomes and Subchondral Sclerosis Following Distraction Arthroplasty of the Ankle Joint
Gianakos A, Haring R, Shimozono Y, Fragomen A, Kennedy J. Effect of Microfracture on Functional Outcomes and Subchondral Sclerosis Following Distraction Arthroplasty of the Ankle Joint. Foot & Ankle International 2020, 41: 631-638. PMID: 32354229, DOI: 10.1177/1071100720917144.Peer-Reviewed Original ResearchConceptsPost-traumatic osteoarthritisDistraction arthroplastyAnkle jointOutcomes of patientsAnkle Outcome ScoreFunctional activity levelBone marrow aspirateFAOS scoresOutcome scoresFunctional outcomeAnkle arthrodesisSubchondral sclerosisBiologic augmentationMarrow aspiratesPatientsLevel IIIPoor candidatesDemographic dataJoint replacementEnd stageArthroplastyAdverse effectsRole of microfracturesActivity levelsSame time interval
2019
No difference in outcomes between femoral fixation methods with hamstring autograft in anterior cruciate ligament reconstruction – A network meta-analysis
Hurley E, Gianakos A, Anil U, Strauss E, Gonzalez-Lomas G. No difference in outcomes between femoral fixation methods with hamstring autograft in anterior cruciate ligament reconstruction – A network meta-analysis. The Knee 2019, 26: 292-301. PMID: 30773253, DOI: 10.1016/j.knee.2019.01.015.Peer-Reviewed Original ResearchConceptsAnterior cruciate ligament reconstructionCruciate ligament reconstructionFemoral fixation methodsInterference screwRandomized control trialTendon autograftACL reconstructionLigament reconstructionKnee stabilityFunctional outcomeFemoral fixationRevision proceduresControl trialFixation methodsFemoral fixation techniquesLevel I studiesMean followGraft failureClinical outcomesI studiesPRISMA guidelinesLevel IPatientsAutograftFixation techniques
2018
Microfracture of subchondral bone leads to persistent subchondral sclerosis and poorer functional outcomes following distraction arthroplasty of the ankle joint while biologic augment may improve recovery times
Gianakos A, Kennedy J. Microfracture of subchondral bone leads to persistent subchondral sclerosis and poorer functional outcomes following distraction arthroplasty of the ankle joint while biologic augment may improve recovery times. Foot & Ankle Orthopaedics 2018, 3: 2473011418s00056. DOI: 10.1177/2473011418s00056.Peer-Reviewed Original ResearchAnkle distractionFunctional outcomeLong-term clinical outcomesSubchondral boneTerm clinical outcomesAnkle Outcome ScoreGood functional outcomeRecords of patientsPoor functional outcomeTreatment of ankleSubchondral bone sclerosisJoint spaceChi-square testingJoint space changesMean followPostoperative rangeAnkle osteoarthritisComplication rateArthroplasty resultsBiologic agentsClinical outcomesAnkle arthritisOutcome scoresMean ageBone sclerosis
2016
The Efficacy of Bisphosphonates with Core Decompression and Mesenchymal Stem Cells Compared with Bisphosphonates Alone in the Treatment of Osteonecrosis of the Hip: A Retrospective Study
Gianakos A, Moya-Angeler J, Duggal S, Zambrana L, Fields K, Mintz D, Cornell C, Lane J. The Efficacy of Bisphosphonates with Core Decompression and Mesenchymal Stem Cells Compared with Bisphosphonates Alone in the Treatment of Osteonecrosis of the Hip: A Retrospective Study. HSS Journal ® 2016, 12: 137-144. PMID: 27385942, PMCID: PMC4916091, DOI: 10.1007/s11420-016-9487-7.Peer-Reviewed Original ResearchModified Harris Hip ScoreVisual analogue scoreTotal hip arthroplastyBisphosphonate therapyCore decompressionMesenchymal stem cellsFunctional outcomeTreatment groupsHip replacementFemoral headEfficacy of bisphosphonatesFicat stage IRadiologic outcome measuresHarris hip scoreYear of diagnosisTreatment of osteonecrosisFuture prospective studiesEarly-stage ONFHInclusion/exclusion criteriaStem cellsJoint preserving proceduresTotal hip replacementProgression of collapseFicat stageInstitution's registryTreatment of Pre-Collapse Stages of Osteonecrosis of the Femoral Head: a Systematic Review of Randomized Control Trials
Villa J, Husain S, van der List J, Gianakos A, Lane J. Treatment of Pre-Collapse Stages of Osteonecrosis of the Femoral Head: a Systematic Review of Randomized Control Trials. HSS Journal ® 2016, 12: 261-271. PMID: 27703421, PMCID: PMC5026659, DOI: 10.1007/s11420-016-9505-9.Peer-Reviewed Original ResearchRandomized clinical trialsFemoral head collapseBone marrow mesenchymal cellsCore decompressionPre-collapse ONFHHead collapseLower riskFemoral headSystematic reviewLow-level evidence studiesMore RCTsQuestions/PurposesThe purposeNew combination therapiesMeta-Analyses (PRISMA) guidelinesRandomized control trialStandardized outcome measuresPreferred Reporting ItemsPre-collapse stageMethodsUsing PubMedRadiologic outcomesBisphosphonate treatmentClinical evidenceMarrow mesenchymal cellsCombination therapyFunctional outcome
2015
Effects of gastrocnemius recession on ankle motion, strength, and functional outcomes: a systematic review and national healthcare database analysis
Gianakos A, Yasui Y, Murawski C, Kennedy J. Effects of gastrocnemius recession on ankle motion, strength, and functional outcomes: a systematic review and national healthcare database analysis. Knee Surgery, Sports Traumatology, Arthroscopy 2015, 24: 1355-1364. PMID: 26685692, DOI: 10.1007/s00167-015-3939-3.Peer-Reviewed Original ResearchConceptsGastrocnemius recessionDorsiflexion rangeFunctional outcomeInclusion criteriaSystematic reviewMean complication rateAnkle dorsiflexion rangeFull-text reviewHealthcare database analysesPeer-reviewed journalsComplication ratePearlDiver databaseEvidence 4Neurologic conditionsEmbase databasesClinical studiesSubtalar jointAnkle motionCadaveric studyGait kinematicsNormal levelsAvailable evidencePatient informationDatabase analysisEvidence scoreFunctional Outcomes of Tibialis Posterior Tendoscopy With Comparison to Magnetic Resonance Imaging
Gianakos A, Ross K, Hannon C, Duke G, Prado M, Kennedy J. Functional Outcomes of Tibialis Posterior Tendoscopy With Comparison to Magnetic Resonance Imaging. Foot & Ankle International 2015, 36: 812-819. PMID: 25759276, DOI: 10.1177/1071100715576485.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingPosterior tendon pathologyTibialis posterior tendonMean preoperative scoreMean postoperative scorePreoperative MRI findingsTendon pathologyFunctional outcomePreoperative scoresMRI findingsPostoperative scoresShort Form-12 (SF-12) general health questionnaireLevel IV case seriesResonance imagingAnkle Outcome ScoreSF-12 scoresTraditional open approachGeneral Health QuestionnairePartial-thickness tearsEffective imaging techniqueSensitive diagnostic toolPosterior tendonPreoperative symptomsPatient ageTendon subluxation