Modified blood cell GAP model as a prognostic biomarker in idiopathic pulmonary fibrosis
Kreuter M, Lee J, Tzouvelekis A, Oldham J, Molyneaux P, Weycker D, Atwood M, Samara K, Kirchgässler K, Maher T. Modified blood cell GAP model as a prognostic biomarker in idiopathic pulmonary fibrosis. ERJ Open Research 2024, 10: 00666-2023. PMID: 39076530, PMCID: PMC11284599, DOI: 10.1183/23120541.00666-2023.Peer-Reviewed Original ResearchIdiopathic pulmonary fibrosisWhite blood cellsRed blood cellsNeutrophil countMonocyte countPulmonary fibrosisHemoglobin levelsRandomised phase III trialBaseline white blood cellC-statisticIPF outcomesBlood cellsTrials of pirfenidoneIdiopathic pulmonary fibrosis progressionImprove prediction of outcomeRed blood cell variablesBlood cell countPredictive of outcomeStudy outcomesRed blood cell parametersMortality prediction toolRespiratory-related hospitalisationEosinophil countRetrospective analysisMultivariate analysis