Pathogenesis of Acute Tubulointerstitial Nephritis
Aron A, Krishnan N, Shirali A. Pathogenesis of Acute Tubulointerstitial Nephritis. 2022, 21-47. DOI: 10.1007/978-3-030-93438-5_3.ChaptersAcute tubulointerstitial nephritisImmune systemTubulointerstitial nephritisRecognition of neoantigensHigh blood flowImmune system activationFinal common pathwayProximal tubule cellsRelease of damageInnate immune systemKidney tubulointerstitial fibrosisInflammatory infiltrationTubulointerstitial fibrosisInflammatory pathwaysTubular reabsorptionImmune responseMetabolic insultsReabsorptive capacityBlood flowSystem activationToxin exposureTubule cellsElevated intracellular concentrationsCell damagePathogenesis