2019
Beyond the Window: Patient Characteristics and Geographic Locations Associated with Late Prenatal Care in Women Eligible for 17-P Preterm Birth Prevention
Wheeler S, DeNoble A, Wynn C, Weaver K, Swamy G, Janko M, Lantos P. Beyond the Window: Patient Characteristics and Geographic Locations Associated with Late Prenatal Care in Women Eligible for 17-P Preterm Birth Prevention. Journal Of Racial And Ethnic Health Disparities 2019, 6: 563-569. PMID: 30632084, DOI: 10.1007/s40615-018-00555-8.Peer-Reviewed Original ResearchConceptsLate presentationPreterm birthGestational ageSingle academic medical centerPatient-level risk factorsIndex pregnancy outcomeRisk of presentationMean gestational agePreterm birth preventionRetrospective cohort studySpontaneous preterm birthLate prenatal careYoung maternal ageRisk of recurrenceWeeks of pregnancyLater gestational agesEarly prenatal care initiationPrenatal care initiationAcademic medical centerBirth preventionCohort studyCurrent smokingLate presentersPatient characteristicsPregnancy outcomes
2011
Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation
Denoble AE, Huffman KM, Stabler TV, Kelly SJ, Hershfield MS, McDaniel GE, Coleman RE, Kraus VB. Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation. Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 108: 2088-2093. PMID: 21245324, PMCID: PMC3033282, DOI: 10.1073/pnas.1012743108.Peer-Reviewed Original ResearchConceptsIL-18OA severityIL-1βUric acidOA progressionSynovial fluid IL-1βCohort of subjectsKnee OA severityInnate immune systemKnee osteoarthritisBone scintigraphyNLRP3 inflammasomeOA pathologyInflammasome activationDanger signalsImmune systemOsteoarthritisRadiographsSeverityPotential involvementInflammasomeProgressionScintigraphyNLRP3Cytokines