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Ania Jastreboff, MD, PhD

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About

Titles

Associate Professor of Medicine (Endocrinology)

Director, Yale Obesity Research Center (Y-Weight); Co-Director, Yale Center for Weight Management; Medical Director, Yale Stress Center

Biography

Ania M. Jastreboff, MD, PhD is an Associate Professor in Medicine and Pediatrics at Yale School of Medicine. She serves as the director of the Yale Obesity Research Center (Y-Weight) and the co-director of the Yale Center for Weight Management. She is trained in both adult endocrinology and pediatric endocrinology, is an obesity medicine physician-scientist, and an international leader in research and clinical application of anti-obesity pharmacotherapeutics. Her work has included working to develop Obesity Clinical Practice Guidelines (AACE/ACE 2016), serving on the Board of Directors for the American Board of Obesity Medicine, educating the next generation of Obesity Medicine physicians by teaching at national and international obesity treatment courses, and conducting cutting-edge clinical-translational obesity research. Her research includes large, multi-center clinical outcomes trials using novel anti-obesity pharmacotherapeutics and studies examining the neurobiology underlying obesity and mechanisms of anti-obesity medications (supported by the NIH/NIDDK). Recently, she has served as lead author for trials investigating potential novel nutrient-stimulated hormone-based therapies for obesity including dual hormone receptor agonist tirzepatide (NEJM) a novel GIP/GLP-1 receptor agonist (Jastreboff, et al., NEJM, 2022) and triple hormone receptor agonist retatrutide (NEJM) a novel GIP/GLP-1/Glucagon receptor agonist (Jastreboff, et al., NEJM, 2023). Dr. Jastreboff thoughtfully advocates for compassionate care for patients with obesity and was recently interviewed Oprah.

Videos of Dr. Jastreboff and colleagues from the NEJM about:

- What causes obesity: https://www.nejm.org/doi/full/...

- Supporting patients with obesity: https://www.nejm.org/doi/full/...

- Medications and surgery for obesity treatment: https://www.nejm.org/doi/full/...

Yale video with Dr. Jastreboff about anti-obesity medications and the biology of obesity.

Podcast (Yale Talk) with the president of Yale University, Dr. Peter Salovey, speaking with Dr. Jastreboff.

Clinically, Dr. Jastreboff specializes in sophisticated use of anti-obesity medication combinations to help patients reach their weight and health goals.

Appointments

  • Endocrinology

    Associate Professor on Term
    Primary

Other Departments & Organizations

Education & Training

Student - Yale Advanced Emerging Leaders
Yale University (2023)
Yale Public Voices Fellowship
Yale University (2022)
Clinical Scholar
Yale University School of Medicine (2013)
YCCI Clinical Research Scholar
Yale School of Medicine (2013)
PhD
Yale University Graduate School of Arts and Sciences, Investigative medicine (2012)
Neuromanaging in Psychiatry
Yale School of Medicine (2011)
Postdoctoral Fellowship
Yale School of Medicine (2011)
Postdoctoral Fellowship
Yale School of Medicine (2011)
Food Policy and Science
Yale University (2010)
Learning to Mentor the next generation of scientists
Yale School of Medicine (2009)
Nutrition and Chronic Disease
Yale University (2009)
Chief Resident
University of Maryland (2006)
Residency
University of Maryland School of Medicine (2006)
Intern
University of Maryland (2003)
MD
University of Maryland at Baltimore (2002)
BA
Bucknell University, Art History/Major, Music/Minor. Magna cum laude (1998)

Research

Overview

obesity and cancer; anti-obesity pharmacotherapy; cancer prevention and risk reduction

Medical Research Interests

Obesity; Weight Loss

Public Health Interests

Obesity

Research at a Glance

Yale Co-Authors

Frequent collaborators of Ania Jastreboff's published research.

Publications

2024

Clinical Trials

Current Trials

Academic Achievements & Community Involvement

  • activity

    The Obesity Society

  • activity

    The Endocrine Society

  • activity

    ADA (American Diabetes Association)

  • activity

    Obesity - National Childhood Obesity Awareness Month Special Issue

  • activity

    Diabetes Care

Clinical Care

Overview

Ania M. Jastreboff, MD, PhD, is an adult and pediatric endocrinologist with expertise in obesity medicine and weight management. She cares for patients who have prediabetes, insulin resistance, metabolic syndrome, and type 1 and type 2 diabetes.

Dr. Jastrebroff, who is director of the Yale Obesity Research Center (Y-Weight), says she empathizes with patients who struggle to lose weight or maintain weight loss. “Carrying excess weight and having obesity is not a lifestyle choice. Obesity is a chronic disease and should be treated with the same vigor and integrity as other chronic diseases,” she says. “We are in the infancy of our understanding of the mechanisms that underlie obesity. Many novel treatments are under development, including new anti-obesity medications, endoscopic procedures, and the refining of behavioral and surgical interventions.”

An assistant professor of medicine (endocrinology) and of pediatrics (endocrinology) at Yale School of Medicine, Dr. Jastrebroff says one of her goals is to conduct clinic research that will lead to better treatments for obesity and also have a clear public health impact in mitigating the obesity “pandemic.”

Clinical Specialties

Obesity Medicine; Pediatric Endocrinology & Diabetes; Diabetes Medicine & Management; Endocrinology

Fact Sheets

Board Certifications

  • Obesity Medicine

    Certification Organization
    AB of Obesity Medicine
    Original Certification Date
    2016
  • Endocrinology Diabetes & Metabolism

    Certification Organization
    AB of Internal Medicine
    Original Certification Date
    2012

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Contacts

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