2016
A Comparison of the Roche Cobas HPV Test With the Hybrid Capture 2 Test for the Detection of High-Risk Human Papillomavirus Genotypes
Levi AW, Bernstein JI, Hui P, Duch K, Schofield K, Chhieng DC. A Comparison of the Roche Cobas HPV Test With the Hybrid Capture 2 Test for the Detection of High-Risk Human Papillomavirus Genotypes. Archives Of Pathology & Laboratory Medicine 2016, 140: 153-7. PMID: 26910220, DOI: 10.5858/arpa.2015-0027-oa.Peer-Reviewed Original ResearchConceptsHigh-risk human papillomavirusHuman papillomavirus assaysCobas human papillomavirus (HPV) testHigh-risk human papillomavirus DNAHybrid Capture 2 testHuman papillomavirus testingHuman papillomavirus testHuman papillomavirus DNAHuman papillomavirusPapillomavirus DNAHigh-risk human papillomavirus genotypesRoche cobas HPV testRoche CobasSurePath preparationsThinPrep specimensDiscordant resultsHybrid captureCobas HPV TestHuman papillomavirus resultsLiquid-based cytology samplesHybrid Capture 2Human papillomavirus genotypesLiquid-based preparationsHPV testCapture 2
2014
Methylation of Twelve CpGs in Human Papillomavirus Type 16 (HPV16) as an Informative Biomarker for the Triage of Women Positive for HPV16 Infection
Brandsma JL, Harigopal M, Kiviat NB, Sun Y, Deng Y, Zelterman D, Lizardi PM, Shabanova VS, Levi A, Yaping T, Hu X, Feng Q. Methylation of Twelve CpGs in Human Papillomavirus Type 16 (HPV16) as an Informative Biomarker for the Triage of Women Positive for HPV16 Infection. Cancer Prevention Research 2014, 7: 526-533. PMID: 24556390, DOI: 10.1158/1940-6207.capr-13-0354.Peer-Reviewed Original ResearchConceptsCervical intraepithelial neoplasiaCytology samplesCutoff scoreColposcopy of womenCervical cancer preventionManagement of womenDetection of CIN3Cervical cytology samplesHuman papillomavirus type 16Human papillomavirus type 16 DNAMethylation biomarkersPapillomavirus type 16Histologic severityIntraepithelial neoplasiaCervical cancerHPV16 infectionCancer preventionDNA bisulfite sequencingType 16Prognostic potentialAccurate biomarkersProspective biomarkersScreening testInformative biomarkersBiomarkers
2011
Use of high‐risk human papillomavirus testing in patients with low‐grade squamous intraepithelial lesions
Levi AW, Harigopal M, Hui P, Schofield K, Chhieng DC. Use of high‐risk human papillomavirus testing in patients with low‐grade squamous intraepithelial lesions. Cancer Cytopathology 2011, 119: 228-234. PMID: 21732551, DOI: 10.1002/cncy.20172.Peer-Reviewed Original ResearchConceptsLow-grade squamous intraepithelial lesionsHR-HPV testingHPV testingCIN 2Colposcopy rateHR-HPVRelative light units/cutoffCervical intraepithelial neoplasia 2High-risk human papillomavirusHR-HPV statusRLU/COIntraepithelial neoplasia 2Hybrid Capture 2Squamous intraepithelial lesionsCIN 1 lesionsLarge teaching hospitalNegative predictive valueLSIL cytologyHPV statusIntraepithelial lesionsCapture 2Human papillomavirusTeaching hospitalCytologic diagnosisSevere lesions
2003
Atypical squamous cells of undetermined significance in liquid‐based cytologic specimens
Levi AW, Kelly DP, Rosenthal DL, Ronnett BM. Atypical squamous cells of undetermined significance in liquid‐based cytologic specimens. Cancer 2003, 99: 191-197. PMID: 12925979, DOI: 10.1002/cncr.11507.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overColposcopyCost-Benefit AnalysisDNA, ViralFemaleFollow-Up StudiesHumansMiddle AgedModels, StatisticalPapanicolaou TestPapillomaviridaePapillomavirus InfectionsPatient Care PlanningPolymerase Chain ReactionPractice Guidelines as TopicSensitivity and SpecificityTumor Virus InfectionsUterine Cervical DysplasiaUterine Cervical NeoplasmsVaginal SmearsConceptsLow-grade squamous intraepithelial lesionsSquamous intraepithelial lesionsHigh-grade squamous intraepithelial lesionsAtypical squamous cellsHPV test resultsHigh-grade lesionsASCUS smearsHPV-positive smearsIntraepithelial lesionsSquamous cellsUndetermined significanceHuman papillomavirus (HPV) DNA testingASCUS interpretationHigh-risk HPV typesHPV-positive casesHPV DNA testingHigh-risk typesLiquid-based Pap smearsLow-grade lesionsDNA testingColposcopy triageHPV testingASCUS cytologyHPV typesPap smear