2015
Detection and Genotype of High-Risk Human Papillomavirus in Fine-Needle Aspirates of Patients With Metastatic Squamous Cell Carcinoma Is Helpful in Determining Tumor Origin
Baldassarri R, Aronberg R, Levi AW, Yarbrough WG, Kowalski D, Chhieng D. Detection and Genotype of High-Risk Human Papillomavirus in Fine-Needle Aspirates of Patients With Metastatic Squamous Cell Carcinoma Is Helpful in Determining Tumor Origin. American Journal Of Clinical Pathology 2015, 143: 694-700. PMID: 25873503, DOI: 10.1309/ajcpcza4pszcfhq4.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaCobas 4800 systemRoche cobas 4800 systemMetastatic squamous cell carcinomaFine needle aspiratesHuman papillomavirusHR-HPVCell carcinomaHPV 16High-risk (HR) HPVSquamous cell carcinoma originatingHigh-risk human papillomavirusNeck squamous cell carcinomaHPV 16/18 genotypesHR-HPV testingHR-HPV detectionHR-HPV resultsCorresponding histologic specimensLeft parapharyngeal massElectronic health recordsCarcinoma originatingMediastinal lymphadenopathyNegative HNSCCProspective studyHistologic material
2014
Methylation of Twelve CpGs in Human Papillomavirus Type 16 (HPV16) as an Informative Biomarker for the Triage of Women Positive for HPV16 Infection
Brandsma JL, Harigopal M, Kiviat NB, Sun Y, Deng Y, Zelterman D, Lizardi PM, Shabanova VS, Levi A, Yaping T, Hu X, Feng Q. Methylation of Twelve CpGs in Human Papillomavirus Type 16 (HPV16) as an Informative Biomarker for the Triage of Women Positive for HPV16 Infection. Cancer Prevention Research 2014, 7: 526-533. PMID: 24556390, DOI: 10.1158/1940-6207.capr-13-0354.Peer-Reviewed Original ResearchConceptsCervical intraepithelial neoplasiaCytology samplesCutoff scoreColposcopy of womenCervical cancer preventionManagement of womenDetection of CIN3Cervical cytology samplesHuman papillomavirus type 16Human papillomavirus type 16 DNAMethylation biomarkersPapillomavirus type 16Histologic severityIntraepithelial neoplasiaCervical cancerHPV16 infectionCancer preventionDNA bisulfite sequencingType 16Prognostic potentialAccurate biomarkersProspective biomarkersScreening testInformative biomarkersBiomarkers