2022
Prediction of Adverse Pathology at Radical Prostatectomy in Grade Group 2 and 3 Prostate Biopsies Using Machine Learning.
Paulson N, Zeevi T, Papademetris M, Leapman MS, Onofrey JA, Sprenkle PC, Humphrey PA, Staib LH, Levi AW. Prediction of Adverse Pathology at Radical Prostatectomy in Grade Group 2 and 3 Prostate Biopsies Using Machine Learning. JCO Clinical Cancer Informatics 2022, 6: e2200016. PMID: 36179281, DOI: 10.1200/cci.22.00016.Peer-Reviewed Original ResearchConceptsGrade group 2Prostate biopsyRadical prostatectomyAdverse outcomesGroup 2GG-2Core prostate biopsyProstate cancer outcomesPatient's clinical riskClinical risk assessmentCore needle biopsyOngoing clinical needAdverse outcome predictionRetrospective reviewAdverse pathologyCAPRA scoreEntire cohortCancer outcomesPathologic diagnosisNeedle biopsyClinical riskDisease outcomeProstate cancerBiopsyDisease one
2021
An independent assessment of an artificial intelligence system for prostate cancer detection shows strong diagnostic accuracy
Perincheri S, Levi AW, Celli R, Gershkovich P, Rimm D, Morrow JS, Rothrock B, Raciti P, Klimstra D, Sinard J. An independent assessment of an artificial intelligence system for prostate cancer detection shows strong diagnostic accuracy. Modern Pathology 2021, 34: 1588-1595. PMID: 33782551, PMCID: PMC8295034, DOI: 10.1038/s41379-021-00794-x.Peer-Reviewed Original ResearchConceptsMemorial Sloan-Kettering Cancer CenterCore biopsyPredictive valueDiagnostic accuracyProstate core needle biopsiesCore needle biopsySurgical pathology practiceNegative predictive valueProstate core biopsiesPositive predictive valueProstate cancer detectionStrong diagnostic accuracyPoor quality scansCancer detectionCancer CenterProstate biopsyLeading causeNeedle biopsyTransrectal approachProstate cancerProstatic adenocarcinomaProstate carcinomaBiopsyPathology practiceProstate
2000
Pseudohyperplastic Prostatic Adenocarcinoma on Needle Biopsy and Simple Prostatectomy
Levi A, Epstein J. Pseudohyperplastic Prostatic Adenocarcinoma on Needle Biopsy and Simple Prostatectomy. The American Journal Of Surgical Pathology 2000, 24: 1039-1046. PMID: 10935644, DOI: 10.1097/00000478-200008000-00001.Peer-Reviewed Original ResearchConceptsNeedle biopsyProstatic adenocarcinomaSimple prostatectomyMalignant diagnosisHigh molecular weight keratinSurgical pathology filesBenign hyperplastic glandsJohns Hopkins HospitalDiagnosis of cancerPathology filesTransurethral resectionPapillary infoldingsHyperplastic glandsAtypical glandsImmunohistochemical stainsConsult casesWeight keratinBiopsyCorpora amylaceaFrequent nucleoliHistologic attributesAdenocarcinomaBenign featuresCancerNuclear enlargement