2000
Muscarinic Activation of BK Channels Induces Membrane Oscillations in Glioma Cells and Leads to Inhibition of Cell Migration
Bordey A, Sontheimer H, Trouslard J. Muscarinic Activation of BK Channels Induces Membrane Oscillations in Glioma Cells and Leads to Inhibition of Cell Migration. The Journal Of Membrane Biology 2000, 176: 31-40. PMID: 10882426, DOI: 10.1007/s00232001073.Peer-Reviewed Original ResearchConceptsPatch-clamp recordingsGlioma cellsAstrocytoma cellsCell migrationCultured human astrocytoma cellsIntracellular free calcium concentrationACh receptor agonistsFree calcium concentrationHuman astrocytoma cellsRelease of Ca2Glioma cell migrationMuscarinic activationMuscarinic antagonistCerebral tumorsMuscarinic receptorsReceptor agonistBath applicationActivate Ca2Intracellular injectionCerebrospinal fluidACh applicationAcetylcholineBiphasic increaseIntracellular storesExternal calcium
1994
Mobilization of intracellular calcium by substance p in a human astrocytoma cell line (U‐373 MG)
Bordey A, Feltz P, Trouslard J. Mobilization of intracellular calcium by substance p in a human astrocytoma cell line (U‐373 MG). Glia 1994, 11: 277-283. PMID: 7525479, DOI: 10.1002/glia.440110309.Peer-Reviewed Original ResearchConceptsSubstance PReceptor agonistConcentrations of SPEffects of SPIntracellular free calcium concentrationSelective receptor agonistsNK1 receptor agonistNM substance PIntracellular calcium poolsFura-2 acetoxymethylesterHuman astrocytoma cell lineStable basal levelExtracellular calcium ionsFree calcium concentrationAstrocytoma cell linesHuman astrocytoma cellsPertussis treatmentNK1 receptorsIntracellular calciumCalcium poolMaximal effectCytosolic calciumAstrocytoma cellsBasal levelsCalcium concentration