Differential Inhibition of Glial K+ Currents by 4-AP
Bordey A, Sontheimer H. Differential Inhibition of Glial K+ Currents by 4-AP. Journal Of Neurophysiology 1999, 82: 3476-3487. PMID: 10601476, DOI: 10.1152/jn.1999.82.6.3476.Peer-Reviewed Original ResearchMeSH Keywords4-AminopyridineAction PotentialsAnimalsAstrocytesCells, CulturedDelayed Rectifier Potassium ChannelsElectrophysiologyLarge-Conductance Calcium-Activated Potassium ChannelsNeurogliaPatch-Clamp TechniquesPotassium Channel BlockersPotassium ChannelsPotassium Channels, Calcium-ActivatedPotassium Channels, Inwardly RectifyingPotassium Channels, Voltage-GatedRatsRats, Sprague-DawleySpinal CordTetraethylammoniumConceptsAcute spinal cord slicesSpinal cord slicesConcentration-dependent blockPotassium channel typesType currentsDose-dependent inhibitorNeuronal action potentialsCord slicesSpinal cordChannel blockersEpileptiform dischargesBrain slicesAction potentialsHomeostatic functionsA-currentAstrocytesDifferential inhibitionRepolarizationMembrane potentialChannel typesSlicesBlockersGlialCord