The Notch pathway in CNS homeostasis and neurodegeneration
Ho DM, Artavanis‐Tsakonas S, Louvi A. The Notch pathway in CNS homeostasis and neurodegeneration. WIREs Mechanisms Of Disease 2019, 9: e358. PMID: 31502763, DOI: 10.1002/wdev.358.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCentral Nervous SystemHomeostasisHumansMutationNeurodegenerative DiseasesReceptors, NotchSignal TransductionConceptsNervous system developmentCNS homeostasisNotch pathway activityNeurodegenerative diseasesCerebral autosomal dominant arteriopathyAcute brain traumaChronic neurodegenerative conditionsProgressive neurodegenerative diseaseAutosomal dominant arteriopathyCellular contextCentral nervous systemAmyotrophic lateral sclerosisNotch signalsAdult organismNotch activityNotch pathwayNeural developmentMultiple sclerosisAdult neurogenesisBrain traumaPathway activitySubcortical infarctsLateral sclerosisNOTCH3 mutationsHereditary stroke