2019
The Notch pathway in CNS homeostasis and neurodegeneration
Ho DM, Artavanis‐Tsakonas S, Louvi A. The Notch pathway in CNS homeostasis and neurodegeneration. WIREs Mechanisms Of Disease 2019, 9: e358. PMID: 31502763, DOI: 10.1002/wdev.358.Peer-Reviewed Original ResearchConceptsNervous system developmentCNS homeostasisNotch pathway activityNeurodegenerative diseasesCerebral autosomal dominant arteriopathyAcute brain traumaChronic neurodegenerative conditionsProgressive neurodegenerative diseaseAutosomal dominant arteriopathyCellular contextCentral nervous systemAmyotrophic lateral sclerosisNotch signalsAdult organismNotch activityNotch pathwayNeural developmentMultiple sclerosisAdult neurogenesisBrain traumaPathway activitySubcortical infarctsLateral sclerosisNOTCH3 mutationsHereditary stroke
2011
Notch Lineages and Activity in Intestinal Stem Cells Determined by a New Set of Knock-In Mice
Fre S, Hannezo E, Sale S, Huyghe M, Lafkas D, Kissel H, Louvi A, Greve J, Louvard D, Artavanis-Tsakonas S. Notch Lineages and Activity in Intestinal Stem Cells Determined by a New Set of Knock-In Mice. PLOS ONE 2011, 6: e25785. PMID: 21991352, PMCID: PMC3185035, DOI: 10.1371/journal.pone.0025785.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBasic Helix-Loop-Helix Transcription FactorsCell DifferentiationCell LineageClone CellsEnterocytesGene Knock-In TechniquesGene TargetingHomeodomain ProteinsIntegrasesIntestinesKineticsMiceMice, Inbred C57BLMice, TransgenicMicrovilliMultipotent Stem CellsReceptors, NotchSequence Homology, Amino AcidSignal TransductionStem CellsTranscription Factor HES-1Transcription, Genetic