Andrew Solomon, PhD
LecturerCards
About
Research
Publications
2024
Multicenter validation of automated detection of paramagnetic rim lesions on brain MRI in multiple sclerosis
Chen L, Ren Z, Clark K, Lou C, Liu F, Cao Q, Manning A, Martin M, Luskin E, O'Donnell C, Azevedo C, Calabresi P, Freeman L, Henry R, Longbrake E, Oh J, Papinutto N, Bilello M, Song J, Kaisey M, Sicotte N, Reich D, Solomon A, Ontaneda D, Sati P, Absinta M, Schindler M, Shinohara R, Cooperative T. Multicenter validation of automated detection of paramagnetic rim lesions on brain MRI in multiple sclerosis. Journal Of Neuroimaging 2024 PMID: 39410780, DOI: 10.1111/jon.13242.Peer-Reviewed Original ResearchParamagnetic rim lesionsArea under the curveRim lesionsMultiple sclerosisPrognosis of MSBiomarkers of chronic inflammationWhite matter lesionsMulticenter settingMulticenter studyMulticenter validationChronic inflammationBrain MRIClinical trialsIdentified lesionsMulticenterMS diagnosisLesionsParamagnetic rimAutomated segmentation methodMRIMRI biomarkersMulticenter datasetDiagnosisSclerosisTeam of trained ratersDifferential diagnosis of suspected multiple sclerosis: global health considerations
Correale J, Solomon A, Cohen J, Banwell B, Gracia F, Gyang T, de Bedoya F, Harnegie M, Hemmer B, Jacob A, Kim H, Marrie R, Mateen F, Newsome S, Pandit L, Prayoonwiwat N, Sahraian M, Sato D, Saylor D, Shi F, Siva A, Tan K, Viswanathan S, Wattjes M, Weinshenker B, Yamout B, Fujihara K. Differential diagnosis of suspected multiple sclerosis: global health considerations. The Lancet Neurology 2024, 23: 1035-1049. PMID: 39304243, DOI: 10.1016/s1474-4422(24)00256-4.Peer-Reviewed Original ResearchConceptsWestern EuropeLatin AmericaEastern EuropeMiddle EastSoutheast AsiaNorth AmericaLatinEuropeHealth considerationsDifferential diagnosis of multiple sclerosisAfricaAmericaPacific regionAsiaDiagnosis of multiple sclerosisDifferential diagnosisCollaborative effortsComprehensive approachMultiple sclerosisEastMedical careDifferential diagnosis of suspected multiple sclerosis: considerations in people from minority ethnic and racial backgrounds in North America, northern Europe, and Australasia
Amezcua L, Rotstein D, Shirani A, Ciccarelli O, Ontaneda D, Magyari M, Rivera V, Kimbrough D, Dobson R, Taylor B, Williams M, Marrie R, Banwell B, Hemmer B, Newsome S, Cohen J, Solomon A, Royal W. Differential diagnosis of suspected multiple sclerosis: considerations in people from minority ethnic and racial backgrounds in North America, northern Europe, and Australasia. The Lancet Neurology 2024, 23: 1050-1062. PMID: 39304244, DOI: 10.1016/s1474-4422(24)00288-6.Peer-Reviewed Original ResearchConceptsSocial determinants of healthDeterminants of healthRacial backgroundSocial determinantsDiagnosis of multiple sclerosisClinical characteristics of peopleCharacteristics of peopleWhite peopleMultiple sclerosisDifferential diagnosisPrevalence of multiple sclerosisSocial challengesMinorityChanging demographicsDifferential diagnosis of multiple sclerosisWhite populationNorthern EuropePeopleEuropeDifferential Diagnosis of Suspected Multiple Sclerosis in Pediatric and Late-Onset Populations
Hua L, Solomon A, Tenembaum S, Scalfari A, Rovira À, Rostasy K, Newsome S, Marrie R, Magyari M, Kantarci O, Hemmer B, Hemingway C, Harnegie M, Graves J, Cohen J, Bove R, Banwell B, Corboy J, Waubant E. Differential Diagnosis of Suspected Multiple Sclerosis in Pediatric and Late-Onset Populations. JAMA Neurology 2024, 81 PMID: 39283621, DOI: 10.1001/jamaneurol.2024.3062.Peer-Reviewed Original ResearchDifferential diagnosisMultiple sclerosisAdult-onset MSClinical presentation of MSPresentation of MSNon-MS diagnosisClinical presentationAdult MSSuspected MSNeuronal injuryLate-onsetConsensus guidanceDiagnostic approachApproximately 5%Age groupsDiagnosisRed flagsMS expertsAgeEarly adulthoodBiological differencesSclerosisOlder adultsYearsAdultsMisdiagnosis and underdiagnosis of multiple sclerosis: A systematic review and meta-analysis
Zürrer W, Cannon A, Ilchenko D, Gaitán M, Granberg T, Piehl F, Solomon A, Ineichen B. Misdiagnosis and underdiagnosis of multiple sclerosis: A systematic review and meta-analysis. Multiple Sclerosis Journal 2024, 30: 1409-1422. PMID: 39246018, DOI: 10.1177/13524585241274527.Peer-Reviewed Original ResearchMeta-analysisSystematic reviewPooled proportionDiagnostic errorsPotential impact of sexMultiple sclerosisMS careMS misdiagnosisHealthcare systemQualitative synthesisImpact patientsMeta-analysesMS diagnosisHighest prevalenceImpact of sexDiagnostic delayUnderdiagnosisFrequency of misdiagnosisDiagnostic challengeMisdiagnosisCareHealthcarePatientsDiagnosisPotential impactMisdiagnosis of Multiple Sclerosis: Past, Present, and Future
Rjeily N, Solomon A. Misdiagnosis of Multiple Sclerosis: Past, Present, and Future. Current Neurology And Neuroscience Reports 2024, 24: 547-557. PMID: 39243340, DOI: 10.1007/s11910-024-01371-w.Peer-Reviewed Original ResearchMS diagnostic criteriaMultiple sclerosisDiagnostic criteriaCentral vein signParamagnetic rim lesionsAssociated with misdiagnosisRecent FindingsRecent studiesMS misdiagnosisMRI findingsEvaluating patientsSuspected MSDiagnostic accuracyRim lesionsFindingsRecent studiesImaging biomarkersMisdiagnosisDiagnostic biomarkersCommon disordersPatientsBiomarkersPotential strategyMultiple sclerosis presenting with paroxysmal symptoms: Patients at the limitations of current diagnostic criteria
Heward K, Roy-Hewitson C, Solomon A. Multiple sclerosis presenting with paroxysmal symptoms: Patients at the limitations of current diagnostic criteria. Multiple Sclerosis Journal 2024, 30: 1566-1570. PMID: 38751226, DOI: 10.1177/13524585241253513.Peer-Reviewed Original ResearchMS diagnostic criteriaCentral nervous systemMultiple sclerosisDiagnostic criteriaClinically isolated syndromeRelapsing remitting MSParoxysmal neurological symptomsLhermitte's phenomenonOptic neuritisClinical attacksTrigeminal neuralgiaCase seriesNeurological symptomsTonic spasmsPatient presentationParoxysmal symptomsPatientsClinical guidanceNervous systemSyndromeOptimal careSymptomsAnecdotal reportsSclerosisNeuralgiaChoroid plexus volume differentiates MS from its mimics
Levit E, Ren Z, Gonzenbach V, Azevedo C, Calabresi P, Cree B, Freeman L, Longbrake E, Oh J, Schindler M, Sicotte N, Reich D, Ontaneda D, Sati P, Cao Q, Shinohara R, Solomon A. Choroid plexus volume differentiates MS from its mimics. Multiple Sclerosis Journal 2024, 30: 1072-1076. PMID: 38481081, PMCID: PMC11288781, DOI: 10.1177/13524585241238094.Peer-Reviewed Original ResearchMultiple Sclerosis Diagnostic Delay and Misdiagnosis
Kaisey M, Solomon A. Multiple Sclerosis Diagnostic Delay and Misdiagnosis. Neurologic Clinics 2024, 42: 1-13. PMID: 37980109, DOI: 10.1016/j.ncl.2023.07.001.Peer-Reviewed Original ResearchConceptsMultiple sclerosis misdiagnosisPatients' clinical outcomesMS diagnostic criteriaMS symptomsClinical outcomesDiagnostic delayDiagnostic challengeDiagnostic criteriaMS misdiagnosisDiagnostic biomarkersAccurate diagnosisIncorrect diagnosisPatientsDiagnosisMisdiagnosisEducational effortsSymptoms
2023
A multicenter pilot study evaluating simplified central vein assessment for the diagnosis of multiple sclerosis
Daboul L, O’Donnell C, Amin M, Rodrigues P, Derbyshire J, Azevedo C, Bar-Or A, Caverzasi E, Calabresi P, Cree B, Freeman L, Henry R, Longbrake E, Oh J, Papinutto N, Pelletier D, Prchkovska V, Raza P, Ramos M, Samudralwar R, Schindler M, Sotirchos E, Sicotte N, Solomon A, Shinohara R, Reich D, Sati P, Ontaneda D. A multicenter pilot study evaluating simplified central vein assessment for the diagnosis of multiple sclerosis. Multiple Sclerosis Journal 2023, 30: 25-34. PMID: 38088067, PMCID: PMC11037932, DOI: 10.1177/13524585231214360.Peer-Reviewed Original ResearchConceptsCentral vein signMultiple sclerosisPositive lesionsInter-rater agreementDiagnosis of MSMagnetic resonance imaging (MRI) biomarkersDiagnostic performancePossible multiple sclerosisInter-rater reliability assessmentGood diagnostic performanceMcDonald criteriaMulticenter studyVein assessmentMean ageVein signImaging biomarkersLesionsMRI sequencesCharacteristic curveSclerosisPatientsDiagnosisAssessmentParticipantsOptimal method