An fMRI Study of the Effects of Psychostimulants on Default-Mode Processing During Stroop Task Performance in Youths With ADHD
Peterson BS, Potenza MN, Wang Z, Zhu H, Martin A, Marsh R, Plessen KJ, Yu S. An fMRI Study of the Effects of Psychostimulants on Default-Mode Processing During Stroop Task Performance in Youths With ADHD. American Journal Of Psychiatry 2009, 166: 1286-1294. PMID: 19755575, PMCID: PMC3289412, DOI: 10.1176/appi.ajp.2009.08050724.Peer-Reviewed Original ResearchConceptsVentral anterior cingulate cortexAnterior cingulate cortexEffects of psychostimulantsCingulate cortexComparison subjectsLateral prefrontal cortexPrefrontal cortexStimulant medicationDefault-mode activityFunctional MRI scansPosterior cingulate cortexVentral anterior cingulateDefault mode processingMedicationsMRI scansAnterior cingulateHealthy comparison youthNormal levelsCortexPsychostimulantsGreater activationFMRI studyGreater reductionLateral prefrontalBrain activityPreliminary evidence for progressive prefrontal abnormalities in adolescents and young adults with bipolar disorder
KALMAR JH, WANG F, SPENCER L, EDMISTON E, LACADIE CM, MARTIN A, CONSTABLE RT, DUNCAN JS, STAIB LH, PAPADEMETRIS X, BLUMBERG HP. Preliminary evidence for progressive prefrontal abnormalities in adolescents and young adults with bipolar disorder. Journal Of The International Neuropsychological Society 2009, 15: 476-481. PMID: 19402934, PMCID: PMC2852397, DOI: 10.1017/s1355617709090584.Peer-Reviewed Original ResearchConceptsAdolescents/young adultsVentral prefrontal cortexBipolar disorderYoung adultsBrain volume changesRostral anterior cingulate cortexPrevious cross-sectional studiesCross-sectional studyAdolescence/young adulthoodHigh-resolution magnetic resonanceAnterior cingulate cortexPreliminary evidenceVolume abnormalitiesHealthy comparison participantsPrefrontal abnormalitiesGreater volume lossCingulate cortexRegional volumesPrefrontal cortexModest sample sizeYoung adulthoodAdultsRostral PFCComparison participantsAbnormalities