2022
Association between prevalence of laboratory-identified Clostridioides difficile infection (CDI) and antibiotic treatment for CDI in US acute-care hospitals, 2019
Xu K, Wu H, Li Q, Edwards J, O’Leary E, Leaptrot D, Benin A. Association between prevalence of laboratory-identified Clostridioides difficile infection (CDI) and antibiotic treatment for CDI in US acute-care hospitals, 2019. Infection Control And Hospital Epidemiology 2022, 43: 1847-1852. PMID: 35068404, PMCID: PMC10877317, DOI: 10.1017/ice.2022.6.Peer-Reviewed Original ResearchConceptsClostridioides difficile infectionFirst-line antibioticsAcute care hospitalsCDI prevalenceAntimicrobial useSignificant dose-response associationNational Healthcare Safety NetworkUS acute care hospitalsPositive dose-response relationshipDose-response associationHospital-level variationExtreme discordanceDose-response relationshipMedical school affiliationCDI eventsDifficile infectionAntibiotic treatmentPrevalence ratesHospitalNegative binomial regressionPrevalenceTreatment practicesBinomial regressionInfectionDiscordance
2020
Hospital Microbiologic Culture Results to Predict the Use of Anti–methicillin-Resistant Staphylococcus aureus (MRSA)
Wu H, Kratzer T, Zhou L, Soe M, Edwards J, Neuhauser M, Benin A, Hicks L, Srinivasan A, Pollock D. Hospital Microbiologic Culture Results to Predict the Use of Anti–methicillin-Resistant Staphylococcus aureus (MRSA). Infection Control And Hospital Epidemiology 2020, 41: s40-s40. DOI: 10.1017/ice.2020.521.Peer-Reviewed Original ResearchAnti-MRSA agentsNational Healthcare Safety NetworkPositive infectionsMicrobiologic culture resultsInfection burdenAntimicrobial useHospital characteristicsCulture resultsStandardized antimicrobial administration ratioStaphylococcus aureusRisk adjustmentLower respiratory specimensIntensive care unitAcute care hospitalsQuinupristin/dalfopristinResistant Staphylococcus aureusMedical school affiliationAU ratesIntravenous vancomycinMicrobiologic dataCare unitDay patientsRespiratory specimensAntimicrobial daysHigh prevalence