2020
Model-based evaluation of the microhemodynamic effects of PEGylated HBOC molecules in the rat brain cortex: a laser speckle imaging study.
Portörő I, Mukli P, Kocsis L, Hermán P, Caccia D, Perrella M, Mozzarelli A, Ronda L, Mathe D, Eke A. Model-based evaluation of the microhemodynamic effects of PEGylated HBOC molecules in the rat brain cortex: a laser speckle imaging study. Biomedical Optics Express 2020, 11: 4150-4175. PMID: 32923034, PMCID: PMC7449705, DOI: 10.1364/boe.388089.Peer-Reviewed Original ResearchHemoglobin-based oxygen carriersLaser speckle contrastSpeckle contrastSpatial dispersionAdverse effectsEuro-pegInfrared ImagingRed blood cell velocityRat brain cortexBlood cell velocityPotential adverse effectsNitric oxide scavengingVascular resistanceAdverse eventsBrain microcirculationBrain cortexFractional changeTissue hematocritPlatelet aggregationImaging studiesCell velocityClinical applicationSignificant differencesExtravasationDispersion
2009
Fractal Characterization of Complexity in Dynamic Signals: Application to Cerebral Hemodynamics
Herman P, Kocsis L, Eke A. Fractal Characterization of Complexity in Dynamic Signals: Application to Cerebral Hemodynamics. Methods In Molecular Biology 2009, 489: 23-40. PMID: 18839086, DOI: 10.1007/978-1-59745-543-5_2.Peer-Reviewed Original ResearchConceptsCerebral hemodynamicsBrain cortexRat brain cortexLaser Doppler flowmetryAge-related stiffeningFunctional magnetic resonanceHemodynamic brain signalsDoppler flowmetryCerebral vasculatureTemporal lobeHuman studiesState of pathologyGray matterParenchymal regionsHemodynamic signalsHemodynamicsHuman brainCortexMagnetic resonanceMedical significance