2020
Model-based evaluation of the microhemodynamic effects of PEGylated HBOC molecules in the rat brain cortex: a laser speckle imaging study.
Portörő I, Mukli P, Kocsis L, Hermán P, Caccia D, Perrella M, Mozzarelli A, Ronda L, Mathe D, Eke A. Model-based evaluation of the microhemodynamic effects of PEGylated HBOC molecules in the rat brain cortex: a laser speckle imaging study. Biomedical Optics Express 2020, 11: 4150-4175. PMID: 32923034, PMCID: PMC7449705, DOI: 10.1364/boe.388089.Peer-Reviewed Original ResearchHemoglobin-based oxygen carriersLaser speckle contrastSpeckle contrastSpatial dispersionAdverse effectsEuro-pegInfrared ImagingRed blood cell velocityRat brain cortexBlood cell velocityPotential adverse effectsNitric oxide scavengingVascular resistanceAdverse eventsBrain microcirculationBrain cortexFractional changeTissue hematocritPlatelet aggregationImaging studiesCell velocityClinical applicationSignificant differencesExtravasationDispersion
2018
Impact of Healthy Aging on Multifractal Hemodynamic Fluctuations in the Human Prefrontal Cortex
Mukli P, Nagy Z, Racz FS, Herman P, Eke A. Impact of Healthy Aging on Multifractal Hemodynamic Fluctuations in the Human Prefrontal Cortex. Frontiers In Physiology 2018, 9: 1072. PMID: 30147657, PMCID: PMC6097581, DOI: 10.3389/fphys.2018.01072.Peer-Reviewed Original ResearchCerebral hemodynamicsHemodynamic fluctuationsElderly groupCerebral hemodynamic fluctuationsNon-neuronal componentsMajority of subjectsNeurovascular couplingElderly subjectsHuman prefrontal cortexHealthy volunteersBrain cortexHemodynamic influenceYounger groupNeural functionPrefrontal cortexHealthy agingHemodynamicsNeural activitySlow componentCortex
2009
Fractal Characterization of Complexity in Dynamic Signals: Application to Cerebral Hemodynamics
Herman P, Kocsis L, Eke A. Fractal Characterization of Complexity in Dynamic Signals: Application to Cerebral Hemodynamics. Methods In Molecular Biology 2009, 489: 23-40. PMID: 18839086, DOI: 10.1007/978-1-59745-543-5_2.Peer-Reviewed Original ResearchConceptsCerebral hemodynamicsBrain cortexRat brain cortexLaser Doppler flowmetryAge-related stiffeningFunctional magnetic resonanceHemodynamic brain signalsDoppler flowmetryCerebral vasculatureTemporal lobeHuman studiesState of pathologyGray matterParenchymal regionsHemodynamic signalsHemodynamicsHuman brainCortexMagnetic resonanceMedical significance
1999
Fractal Analysis of Spontaneous Fluctuations in Human Cerebral Hemoglobin Content and its Oxygenation Level Recorded by NIRS
Eke A, Hermán P. Fractal Analysis of Spontaneous Fluctuations in Human Cerebral Hemoglobin Content and its Oxygenation Level Recorded by NIRS. Advances In Experimental Medicine And Biology 1999, 471: 49-55. PMID: 10659131, DOI: 10.1007/978-1-4615-4717-4_7.Peer-Reviewed Original ResearchConceptsBrain cortex
1993
Multiparametric Imaging of Microregional Circulation over the Brain Cortex by Videoreflectometry
Eke A. Multiparametric Imaging of Microregional Circulation over the Brain Cortex by Videoreflectometry. Advances In Experimental Medicine And Biology 1993, 333: 183-191. PMID: 8362659, DOI: 10.1007/978-1-4899-2468-1_16.Peer-Reviewed Original ResearchConceptsBlood flowBrain cortexTissue microcirculationLevel of microcirculationMultiparametric imagingNutritive microcirculationParenchymal circulationMean transit timeBlood volumeMultiparametric assessmentMicrocirculationPlasma volumeRepeatable mannerSpatial resolutionTissue elementsFlowVolume flowCapillary networkCortexErythrocytesDiameter of capillariesTransit time
1992
Instrumentation and Technology for Multiparametric Mapping of Intraparenchymal Circulation in the Brain Cortex
Eke A. Instrumentation and Technology for Multiparametric Mapping of Intraparenchymal Circulation in the Brain Cortex. Advances In Experimental Medicine And Biology 1992, 317: 671-678. PMID: 1288187, DOI: 10.1007/978-1-4615-3428-0_80.Peer-Reviewed Original ResearchConceptsBrain cortexSpatial resolutionRepeatable mannerVolume flowEnergy balanceSpatial imagingTechnologyMean transit timeInstrumentationBlood volumeLevel of instrumentationMultiparametric assessmentDischarge hematocritResolution mapsPlasma volumeCapillary bedHigh-resolution mapsCortexMultiparametric mappingMm2
1989
Hematocrit Changes in the Extra- and Intraparenchymal Circulation of the Feline Brain Cortex in the Course of Global Cerebral Ischemia
Eke A. Hematocrit Changes in the Extra- and Intraparenchymal Circulation of the Feline Brain Cortex in the Course of Global Cerebral Ischemia. Advances In Experimental Medicine And Biology 1989, 248: 439-449. PMID: 2782165, DOI: 10.1007/978-1-4684-5643-1_49.Peer-Reviewed Original ResearchConceptsGlobal cerebral ischemiaCerebral ischemiaTissue hematocritMean arterial blood pressureArterial blood pressureIschemic tissue damageCerebrocortical tissueParenchymal circulationBlood pressureArterial hemorrhageBrain cortexIschemic conditionsAltered distribution patternHematocrit changesTissue damageFocal alterationsSignificant heterogeneityIschemiaHematocritControl conditionPresent studyPreliminary studyHemorrhageMicrocirculationCortex
1985
Redistribution of Cerebrocortical Microflow During Increased Neuronal Activity
Eke A. Redistribution of Cerebrocortical Microflow During Increased Neuronal Activity. Advances In Experimental Medicine And Biology 1985, 191: 101-105. PMID: 3832835, DOI: 10.1007/978-1-4684-3291-6_9.Peer-Reviewed Original Research
1983
Integrated Microvessel Diameter and Microregional Blood Content as Determined by Cerebrocortical Video Reflectometry
Eke A. Integrated Microvessel Diameter and Microregional Blood Content as Determined by Cerebrocortical Video Reflectometry. 1983, 249-252. DOI: 10.1007/978-3-7091-4124-3_30.Peer-Reviewed Original Research
1982
Reflectometric Mapping of Microregional Blood Flow and Blood Volume in the Brain Cortex
Eke A. Reflectometric Mapping of Microregional Blood Flow and Blood Volume in the Brain Cortex. Cerebrovascular And Brain Metabolism Reviews 1982, 2: 41-53. PMID: 6801064, DOI: 10.1038/jcbfm.1982.5.Peer-Reviewed Original Research
1981
METHODOLOGY OF THE SIMULTANEOUS, NONDESTRUCTIVE DETERMINATION OF METABOLISM, BLOOD FLOW AND BLOOD VOLUME WITHIN SUPERFICIAL MICROAREAS OF THE BRAIN CORTEX BY MICROFLUOROREFLECTOMETRY
Eke A, Kovách A. METHODOLOGY OF THE SIMULTANEOUS, NONDESTRUCTIVE DETERMINATION OF METABOLISM, BLOOD FLOW AND BLOOD VOLUME WITHIN SUPERFICIAL MICROAREAS OF THE BRAIN CORTEX BY MICROFLUOROREFLECTOMETRY. 1981, 335-341. DOI: 10.1016/b978-0-08-026820-0.50043-3.Peer-Reviewed Original ResearchStability of Oxygen Transmissibility During Ischemia
Eke A, Strong E, Halsey J. Stability of Oxygen Transmissibility During Ischemia. Neurological Research 1981, 3: 211-228. PMID: 6122173, DOI: 10.1080/01616412.1981.11739599.Peer-Reviewed Original Research
1979
Induced hemodilution detected by reflectometry for measuring microregional blood flow and blood volume in cat brain cortex
Eke A, Hutiray G, Kovách A. Induced hemodilution detected by reflectometry for measuring microregional blood flow and blood volume in cat brain cortex. American Journal Of Physiology 1979, 236: h759-h768. PMID: 375750, DOI: 10.1152/ajpheart.1979.236.5.h759.Peer-Reviewed Original Research
1977
Microvessel reactions and NAD-NADH changes in cat brain cortex during cortical stimulation under normo- and hypercapnic conditions.
Gyulai L, Dora E, Eke A, Kovach A. Microvessel reactions and NAD-NADH changes in cat brain cortex during cortical stimulation under normo- and hypercapnic conditions. Acta Anatomica 1977, 183-6. PMID: 202240.Peer-Reviewed Original ResearchCerebrovascular and metabolic reactions at the CBF autoregulatory level evoked by electrical stimulation of the cat brain cortex.
Kovách A, Dóra E, Gyulai L, Eke A. Cerebrovascular and metabolic reactions at the CBF autoregulatory level evoked by electrical stimulation of the cat brain cortex. Acta Anatomica 1977, 371-4. PMID: 202242.Peer-Reviewed Original Research
1976
Correlation between the Redox State, Electrical Activity and Blood Flow in Cat Brain CORTEX During Hemorrhagic Shock
Kovách A, Eke A, Dóra E, Gyulai L. Correlation between the Redox State, Electrical Activity and Blood Flow in Cat Brain CORTEX During Hemorrhagic Shock. Advances In Experimental Medicine And Biology 1976, 75: 289-297. PMID: 189584, DOI: 10.1007/978-1-4684-3273-2_35.Peer-Reviewed Original Research