2022
tDCS induced GABA change is associated with the simulated electric field in M1, an effect mediated by grey matter volume in the MRS voxel
Nandi T, Puonti O, Clarke W, Nettekoven C, Barron H, Kolasinski J, Hanayik T, Hinson E, Berrington A, Bachtiar V, Johnstone A, Winkler A, Thielscher A, Johansen-Berg H, Stagg C. tDCS induced GABA change is associated with the simulated electric field in M1, an effect mediated by grey matter volume in the MRS voxel. Brain Stimulation 2022, 15: 1153-1162. PMID: 35988862, PMCID: PMC7613675, DOI: 10.1016/j.brs.2022.07.049.Peer-Reviewed Original Research
2019
Short-interval intracortical inhibition is decreased in restless legs syndrome across a range of severity
Magalhães S, Queiroz de Paiva J, Kaelin-Lang A, Sterr A, Eckeli A, Winkler A, Fernandes do Prado G, Amaro E, Conforto A. Short-interval intracortical inhibition is decreased in restless legs syndrome across a range of severity. Sleep Medicine 2019, 62: 34-42. PMID: 31539846, DOI: 10.1016/j.sleep.2019.03.021.Peer-Reviewed Original ResearchConceptsShort-interval intracortical inhibitionRLS/WEDCortical thicknessIntracortical inhibitionRestless legs syndrome/Willis-Ekbom diseaseRestless legs syndromePrimary motor cortexWillis-Ekbom diseaseCharacteristic curve analysisGray matter thicknessDiscrimination of participantsIdiopathic mildRange of severityLegs syndromeMotor cortexMagnetic resonance imaging dataMild symptomsSurface-based analysisSeverity ScaleCortical areasMagnetic stimulationWhole brainCurve analysisCharacteristic curveSeverity
2016
Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke
Allman C, Amadi U, Winkler A, Wilkins L, Filippini N, Kischka U, Stagg C, Johansen-Berg H. Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke. Science Translational Medicine 2016, 8: 330re1. PMID: 27089207, PMCID: PMC5388180, DOI: 10.1126/scitranslmed.aad5651.Peer-Reviewed Original ResearchConceptsAnodal transcranial direct current stimulationTranscranial direct current stimulationAction Research Arm TestWolf Motor Function TestMagnetic resonance imagingMotor trainingPremotor cortexIpsilesional motorSham treatmentFunctional magnetic resonance imagingUpper extremity Fugl-Meyer scoreDaily motor trainingLong-term clinical outcomesAnodal tDCS groupFirst unilateral strokeDirect current stimulationIntervention-related increasesFugl-Meyer scoreSham treatment groupMotor Function TestMotor training programPrimary motor cortexStructural magnetic resonance imagingGray matter volumeMotor learning
2015
Striatal activity and reduced white matter increase frontal activity in youths with family histories of alcohol and other substance‐use disorders performing a go/no‐go task
Acheson A, Tagamets M, Winkler A, Rowland L, Mathias C, Wright S, Hong L, Kochunov P, Dougherty D. Striatal activity and reduced white matter increase frontal activity in youths with family histories of alcohol and other substance‐use disorders performing a go/no‐go task. Brain And Behavior 2015, 5: e00352. PMID: 26221573, PMCID: PMC4511289, DOI: 10.1002/brb3.352.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAspartic AcidBrain MappingChildCorpus StriatumExecutive FunctionFamilyFemaleGenetic Predisposition to DiseaseHumansInhibition, PsychologicalLongitudinal StudiesMagnetic Resonance ImagingMaleMotor CortexNeural PathwaysProton Magnetic Resonance SpectroscopyPsychomotor PerformanceSignal Processing, Computer-AssistedSubstance-Related DisordersWhite MatterConceptsSupplementary motor areaSubstance use disordersWhite matter integrityFamily historyFrontal white matter integrityStriatal activityDorsal striatumFrontal cortical activityCortical activitySMA activityFrontal cortical projectionsDrug use disordersDorsal striatal activitySuch family historyDorsal striatum activityCortical projectionsMotor areaElevated riskOngoing longitudinal studyUse disordersWhite matterDownstream projectionsGo/