2023
Mapping Lesion-Related Epilepsy to a Human Brain Network
Schaper F, Nordberg J, Cohen A, Lin C, Hsu J, Horn A, Ferguson M, Siddiqi S, Drew W, Soussand L, Winkler A, Simó M, Bruna J, Rheims S, Guenot M, Bucci M, Nummenmaa L, Staals J, Colon A, Ackermans L, Bubrick E, Peters J, Wu O, Rost N, Grafman J, Blumenfeld H, Temel Y, Rouhl R, Joutsa J, Fox M. Mapping Lesion-Related Epilepsy to a Human Brain Network. JAMA Neurology 2023, 80: 891-902. PMID: 37399040, PMCID: PMC10318550, DOI: 10.1001/jamaneurol.2023.1988.Peer-Reviewed Original ResearchConceptsRisk of epilepsyLesion locationBrain regionsPoststroke epilepsyControl patientsSeizure controlBrain lesionsIndependent cohortBrain networksLesion typeBrain stimulation sitesLesion network mappingLesion-related epilepsyImproved seizure controlDrug-resistant epilepsyCase-control studyBrain stimulation therapyHuman brain networksSpecific brain regionsDifferent lesion typesSpecific brain networksBasal gangliaVascular territoriesStimulation therapyMAIN OUTCOME
2016
Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke
Allman C, Amadi U, Winkler A, Wilkins L, Filippini N, Kischka U, Stagg C, Johansen-Berg H. Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke. Science Translational Medicine 2016, 8: 330re1. PMID: 27089207, PMCID: PMC5388180, DOI: 10.1126/scitranslmed.aad5651.Peer-Reviewed Original ResearchConceptsAnodal transcranial direct current stimulationTranscranial direct current stimulationAction Research Arm TestWolf Motor Function TestMagnetic resonance imagingMotor trainingPremotor cortexIpsilesional motorSham treatmentFunctional magnetic resonance imagingUpper extremity Fugl-Meyer scoreDaily motor trainingLong-term clinical outcomesAnodal tDCS groupFirst unilateral strokeDirect current stimulationIntervention-related increasesFugl-Meyer scoreSham treatment groupMotor Function TestMotor training programPrimary motor cortexStructural magnetic resonance imagingGray matter volumeMotor learning