2023
Structural and functional asymmetry of the neonatal cerebral cortex
Williams L, Fitzgibbon S, Bozek J, Winkler A, Dimitrova R, Poppe T, Schuh A, Makropoulos A, Cupitt J, O’Muircheartaigh J, Duff E, Cordero-Grande L, Price A, Hajnal J, Rueckert D, Smith S, Edwards A, Robinson E. Structural and functional asymmetry of the neonatal cerebral cortex. Nature Human Behaviour 2023, 7: 942-955. PMID: 36928781, DOI: 10.1038/s41562-023-01542-8.Peer-Reviewed Original ResearchConceptsCortical asymmetryHealthy term-born neonatesNeonatal cerebral cortexTerm-born neonatesTerm-equivalent ageHealthy young adultsHuman Connectome ProjectPreterm birthPreterm neonatesNeonatal cortexCerebral cortexTerm cohortFunctional magnetic resonance imagesMagnetic resonance imagesConnectome ProjectBrain asymmetryYoung adultsSignificant differencesNeonatesResonance imagesFunctional asymmetryCortexBirthBiological sexCohort
2017
Anxiety modulates the relation between attention-deficit/hyperactivity disorder severity and working memory-related brain activity
van der Meer D, Hoekstra P, van Rooij D, Winkler A, van Ewijk H, Heslenfeld D, Oosterlaan J, Faraone S, Franke B, Buitelaar J, Hartman C. Anxiety modulates the relation between attention-deficit/hyperactivity disorder severity and working memory-related brain activity. The World Journal Of Biological Psychiatry 2017, 19: 450-460. PMID: 28635543, PMCID: PMC5581282, DOI: 10.1080/15622975.2017.1287952.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnxietyAnxiety DisordersAttention Deficit Disorder with HyperactivityCerebellumChildCognitive DysfunctionCohort StudiesComorbidityCorpus StriatumFemaleFunctional NeuroimagingHumansMagnetic Resonance ImagingMaleMemory, Short-TermSeverity of Illness IndexThalamusYoung AdultConceptsAttention-deficit/hyperactivity disorderCo-occurring anxietyADHD severityNeural activityMemory taskAttention-deficit/hyperactivity disorder severityMemory-related brain activityPresence of ADHDVisuospatial Working Memory TaskWorking Memory TaskLevel of anxietyVSWM tasksMemory loadHyperactivity disorderTask accuracyPrevious theorisingAnxiety severityBrain activityNeurobiological heterogeneityDisorder severityAnxietyWorse performanceInformation gatingYoung adultsNeural pathways
2014
Assessment of whole brain white matter integrity in youths and young adults with a family history of substance‐use disorders
Acheson A, Wijtenburg S, Rowland L, Winkler A, Gaston F, Mathias C, Fox P, Lovallo W, Wright S, Hong L, Dougherty D, Kochunov P. Assessment of whole brain white matter integrity in youths and young adults with a family history of substance‐use disorders. Human Brain Mapping 2014, 35: 5401-5413. PMID: 24867528, PMCID: PMC4206569, DOI: 10.1002/hbm.22559.Peer-Reviewed Original ResearchConceptsSubstance use disordersLower FA valuesFamily historyUse disordersFA valuesCorona radiataWhole-brain white matter integrityYoung adultsFrontostriatal white matter tractsBrain white matter integrityFrontal white matterPosterior corona radiataAnterior corona radiataFractional anisotropy (FA) dataHigher radial diffusivitySuch family historyWhite matter tractsWhite matter integrityAge-related declineImpaired myelinationAxonal myelinationCorpus callosumGeneral populationWhite matterSignificant negative correlation