Cognitive Phenotypes and Endophenotypes: Concepts and Criteria
Bearden C, Winkler A, Karlsgodt K, Bilder R. Cognitive Phenotypes and Endophenotypes: Concepts and Criteria. Innovations In Cognitive Neuroscience 2016, 61-80. DOI: 10.1007/978-1-4614-3846-5_4.Peer-Reviewed Original ResearchCategorical disease phenotypesGenetic mapping studiesDirect drug targetComplex traitsQuantitative traitsDrug targetsPhenotype approachNew phenotypesComplex diseasesSpecific molecular targetsDisease phenotypePhenotypeMolecular targetsNeuropsychiatric TherapeuticsMapping studiesBiological mechanismsCognitive phenotypesNeuroanatomic phenotypesTraitsBiological validityQuantitative assayDiagnostic phenotypesNeural systems levelDramatic advancesHeritability