2014
Adiponectin Gene Polymorphisms and Acute Respiratory Distress Syndrome Susceptibility and Mortality
Ahasic AM, Zhao Y, Su L, Sheu CC, Thompson BT, Christiani DC. Adiponectin Gene Polymorphisms and Acute Respiratory Distress Syndrome Susceptibility and Mortality. PLOS ONE 2014, 9: e89170. PMID: 24586568, PMCID: PMC3929660, DOI: 10.1371/journal.pone.0089170.Peer-Reviewed Original ResearchConceptsARDS casesInsulin resistanceSingle nucleotide polymorphismsCase statusAcute respiratory distress syndrome (ARDS) riskFunctional polymorphismsAnti-inflammatory adipokineAcute respiratory failureDevelopment of ARDSAdiponectin gene polymorphismsMultiple comparisonsAdipokine levelsCause mortalityRespiratory failureAdiponectin levelsCritical illnessConsecutive patientsMultivariable analysisRisk factorsSyndrome riskCardiovascular diseaseAdipose tissueGene polymorphismsARDSMortality
2011
IGF1 and IGFBP3 in acute respiratory distress syndrome
Ahasic AM, Zhai R, Su L, Zhao Y, Aronis KN, Thompson BT, Mantzoros CS, Christiani DC. IGF1 and IGFBP3 in acute respiratory distress syndrome. European Journal Of Endocrinology 2011, 166: 121-129. PMID: 22004906, PMCID: PMC3757506, DOI: 10.1530/eje-11-0778.Peer-Reviewed Original ResearchConceptsAcute respiratory distress syndromeLevels of IGF1Development of ARDSRespiratory distress syndromeIGFBP3 levelsARDS casesDistress syndromePersistent acute respiratory distress syndromeFibrotic lung diseaseSeverity of illnessIntensive care unitCase-cohort studyRelevant clinical covariatesCause mortalityConsecutive patientsCare unitLung diseaseRisk factorsClinical covariatesPlasma IGF1Parent studyCase statusPatientsIGF pathwayDay 60