2016
Update on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunities
Stahl M, Kim TK, Zeidan AM. Update on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunities. World Journal Of Stem Cells 2016, 8: 316-331. PMID: 27822339, PMCID: PMC5080639, DOI: 10.4252/wjsc.v8.i10.316.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsLeukemia stem cellsNormal hematopoietic stem cellsHematopoietic stem cellsAcute myeloid leukemia stem cellsMyeloid leukemia stem cellsStem cellsAcute myeloid leukemiaMultitude of drugsNovel therapeutic agentsCancer stem cellsClinical trialsMyeloid leukemiaTherapeutic windowSelf-renewal pathwaysXenograft modelClinical developmentTherapeutic opportunitiesRational targetTherapeutic agentsLSC biologyAcceptable therapeutic windowDrugsCellsFunctional studiesLeukemia
2014
Stem cells in gastrointestinal cancers: The road less travelled.
Mikhail S, Zeidan A. Stem cells in gastrointestinal cancers: The road less travelled. World Journal Of Stem Cells 2014, 6: 606-13. PMID: 25426257, PMCID: PMC4178260, DOI: 10.4252/wjsc.v6.i5.606.Peer-Reviewed Original ResearchCancer stem cellsGastrointestinal malignanciesNew therapeutic optionsFormation of CSCsGeneration of CSCsRole of dysregulationWnt/β-cateninStem cellsGastrointestinal neoplasmsTherapeutic optionsGastroesophageal tumorsGastrointestinal cancerTherapeutic strategiesTumor growthMalignant cellsMolecular abnormalitiesSignificant optimismCancerCancer resistanceΒ-cateninPatientsMalignancyTransformation growthPrecise targetingPotential utility