2024
Intense exercise increases dopamine transporter and neuromelanin concentrations in the substantia nigra in Parkinson’s disease
de Laat B, Hoye J, Stanley G, Hespeler M, Ligi J, Mohan V, Wooten D, Zhang X, Nguyen T, Key J, Colonna G, Huang Y, Nabulsi N, Patel A, Matuskey D, Morris E, Tinaz S. Intense exercise increases dopamine transporter and neuromelanin concentrations in the substantia nigra in Parkinson’s disease. Npj Parkinson's Disease 2024, 10: 34. PMID: 38336768, PMCID: PMC10858031, DOI: 10.1038/s41531-024-00641-1.Peer-Reviewed Original ResearchDopamine transporterSubstantia nigraDopaminergic neuronsDopamine transporter availabilityNeuroprotective effects of exerciseDopaminergic systemClinical progression of PDEarly PDSubstantiaNeuromelanin contentNigraLoss of dopaminergic neuronsEffects of exerciseNM-MRIDopamineSystem of patientsProgressive loss of dopaminergic neuronsParkinson's diseaseClinical progressionProgression of PDNeuroprotective effectsClinical trialsIntensity exercisePET imagingProgressive loss
2015
Isolated vocal tremor as a focal phenotype of essential tremor: a retrospective case review
Patel A, Frucht SJ. Isolated vocal tremor as a focal phenotype of essential tremor: a retrospective case review. Journal Of Clinical Movement Disorders 2015, 2: 4. PMID: 26788340, PMCID: PMC4711152, DOI: 10.1186/s40734-015-0016-5.Peer-Reviewed Original ResearchVocal tremorFamily historyRetrospective case reviewCurrent diagnostic criteriaLeast mild improvementSodium oxybateSymptom onsetCommon medicationsInitial visitRetrospective reviewTremor improvementClinical syndromeCommon manifestationPrimary diagnosisClinical trialsAction tremorMild improvementVoice disturbanceCommon conditionLimb tremorDiagnostic criteriaAverage ageLower limbsPatientsAlcohol consumption