MEN1 tumor‐suppressor protein localizes to telomeres during meiosis
Suphapeetiporn K, Greally JM, Walpita D, Ashley T, Bale AE. MEN1 tumor‐suppressor protein localizes to telomeres during meiosis. Genes Chromosomes And Cancer 2002, 35: 81-85. PMID: 12203793, DOI: 10.1002/gcc.10113.Peer-Reviewed Original ResearchConceptsSomatic cellsTelomerase activityAbsence of meninTumor suppressor gene MEN1Normal cell physiologyTelomeric protein TRF2Normal telomerase activityTumor suppressor proteinRole of meninMeiotic telomeresTelomere functionProtein TRF2Meiotic cellsTranscriptional activationNuclear proteinsCell physiologyFunctional motifsDifferent proteinsTumor suppressorTelomeresMeninElevated telomerase activityDifferent tissuesJunDCancer predisposition syndrome